Maturation-Promoting Factor
"Maturation-Promoting Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.
| Descriptor ID |
D016200
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.984 D12.644.360.250.580 D12.776.167.200.580 D12.776.476.250.580
|
| Concept/Terms |
Maturation-Promoting Factor- Maturation-Promoting Factor
- Maturation Promoting Factor
- Histone H1 Kinase, M-Phase-Specific
- Histone H1 Kinase, M Phase Specific
- Mitosis-Promoting Factor
- Mitosis Promoting Factor
- Histone H1 Kinase, Growth-Associated
- Histone H1 Kinase, Growth Associated
- M Phase-Promoting Factor
- M Phase Promoting Factor
|
Below are MeSH descriptors whose meaning is more general than "Maturation-Promoting Factor".
Below are MeSH descriptors whose meaning is more specific than "Maturation-Promoting Factor".
This graph shows the total number of publications written about "Maturation-Promoting Factor" by people in this website by year, and whether "Maturation-Promoting Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Maturation-Promoting Factor" by people in Profiles.
-
Du F, Xu J, Zhang J, Gao S, Carter MG, He C, Sung LY, Chaubal S, Fissore RA, Tian XC, Yang X, Chen YE. Beneficial effect of young oocytes for rabbit somatic cell nuclear transfer. Cloning Stem Cells. 2009 Mar; 11(1):131-40.
-
Combelles CM, Fissore RA, Albertini DF, Racowsky C. In vitro maturation of human oocytes and cumulus cells using a co-culture three-dimensional collagen gel system. Hum Reprod. 2005 May; 20(5):1349-58.
-
Sanfins A, Plancha CE, Overstrom EW, Albertini DF. Meiotic spindle morphogenesis in in vivo and in vitro matured mouse oocytes: insights into the relationship between nuclear and cytoplasmic quality. Hum Reprod. 2004 Dec; 19(12):2889-99.
-
Ducibella T, Huneau D, Angelichio E, Xu Z, Schultz RM, Kopf GS, Fissore R, Madoux S, Ozil JP. Egg-to-embryo transition is driven by differential responses to Ca(2+) oscillation number. Dev Biol. 2002 Oct 15; 250(2):280-91.
-
Salamone DF, Damiani P, Fissore RA, Robl JM, Duby RT. Biochemical and developmental evidence that ooplasmic maturation of prepubertal bovine oocytes is compromised. Biol Reprod. 2001 Jun; 64(6):1761-8.
-
Gordo AC, He CL, Smith S, Fissore RA. Mitogen activated protein kinase plays a significant role in metaphase II arrest, spindle morphology, and maintenance of maturation promoting factor activity in bovine oocytes. Mol Reprod Dev. 2001 May; 59(1):106-14.
-
Moos J, Visconti PE, Moore GD, Schultz RM, Kopf GS. Potential role of mitogen-activated protein kinase in pronuclear envelope assembly and disassembly following fertilization of mouse eggs. Biol Reprod. 1995 Sep; 53(3):692-9.
-
Sluder G, Thompson EA, Rieder CL, Miller FJ. Nuclear envelope breakdown is under nuclear not cytoplasmic control in sea urchin zygotes. J Cell Biol. 1995 Jun; 129(6):1447-58.
-
Pal SK, Torry D, Serta R, Crowell RC, Seibel MM, Cooper GM, Kiessling AA. Expression and potential function of the c-mos proto-oncogene in human eggs. Fertil Steril. 1994 Mar; 61(3):496-503.