"Haptens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves cannot elicit an antibody response.
Descriptor ID |
D006241
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MeSH Number(s) |
D23.050.550.480
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Haptens".
Below are MeSH descriptors whose meaning is more specific than "Haptens".
This graph shows the total number of publications written about "Haptens" by people in this website by year, and whether "Haptens" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 1 | 0 | 1 |
2001 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Haptens" by people in Profiles.
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Fuhrmann J, Subramanian V, Thompson PR. Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody. Angew Chem Int Ed Engl. 2015 Dec 01; 54(49):14715-8.
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Rock KL, Benacerraf B, Abbas AK. Pillars article: antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. 1984. J Immunol. 2007 Dec 01; 179(11):7194-205.
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Marraffa J, Guharoy R, Duggan D, Rose F, Nazeer S. Vancomycin-induced thrombocytopenia: a case proven with rechallenge. Pharmacotherapy. 2003 Sep; 23(9):1195-8.
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Kovarik J, Bozzotti P, Tougne C, Davis HL, Lambert PH, Krieg AM, Siegrist CA. Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens. Immunology. 2001 Jan; 102(1):67-76.
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Albuquerque DA, Martins GA, Campos-Neto A, Silva JS. The adjuvant effect of jacalin on the mouse humoral immune response to trinitrophenyl and Trypanosoma cruzi. Immunol Lett. 1999 Jun 01; 68(2-3):375-81.
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Gruchalla RS, Pesenko RD, Do TT, Skiest DJ. Sulfonamide-induced reactions in desensitized patients with AIDS--the role of covalent protein haptenation by sulfamethoxazole. J Allergy Clin Immunol. 1998 Mar; 101(3):371-8.
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Kurt-Jones EA, Liano D, HayGlass KA, Benacerraf B, Sy MS, Abbas AK. The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice. J Immunol. 1988 Jun 01; 140(11):3773-8.
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Flood PM, Friedman A, Freedman J, Horvat B, Reuter P, Ptak W. The role of contrasuppression in tumor regression. Immunol Res. 1988; 7(1):12-22.
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Rock KL, Haber SI, Liano D, Benacerraf B, Abbas AK. Antigen presentation by hapten-specific B lymphocytes. III. Analysis of the immunoglobulin-dependent pathway of antigen presentation to interleukin 1-dependent T lymphocytes. Eur J Immunol. 1986 Nov; 16(11):1407-12.
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Abbas AK, Haber S, Rock KL. Antigen presentation by hapten-specific B lymphocytes. II. Specificity and properties of antigen-presenting B lymphocytes, and function of immunoglobulin receptors. J Immunol. 1985 Sep; 135(3):1661-7.