Connective Tissue Growth Factor
"Connective Tissue Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.
| Descriptor ID |
D055513
|
| MeSH Number(s) |
D12.644.276.200.100 D12.776.467.200.100 D12.776.860.300.200.100 D23.529.237.100
|
| Concept/Terms |
Connective Tissue Growth Factor- Connective Tissue Growth Factor
- Hypertrophic Chondrocyte-Specific Protein 24
- Hypertrophic Chondrocyte Specific Protein 24
- IGF-Binding Protein-Related Protein-2
- IGF Binding Protein Related Protein 2
- IGFBP-rP2
- Insulin-Like Growth Factor Binding Protein 8
- Insulin Like Growth Factor Binding Protein 8
- CCN2 Protein
- IGFBP-8
|
Below are MeSH descriptors whose meaning is more general than "Connective Tissue Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Connective Tissue Growth Factor".
This graph shows the total number of publications written about "Connective Tissue Growth Factor" by people in this website by year, and whether "Connective Tissue Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Connective Tissue Growth Factor" by people in Profiles.
-
Miao X, Fan B, Li R, Zhang S, Lin H. Network Analysis of Depression-Related Transcriptomic Profiles. Neuromolecular Med. 2019 06; 21(2):143-149.
-
Gonzalez D, Rebolledo DL, Correa LM, Court FA, Cerpa W, Lipson KE, van Zundert B, Brandan E. The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model. Hum Mol Genet. 2018 08 15; 27(16):2913-2926.
-
Kiwanuka E, Lee CC, Hackl F, Caterson EJ, Junker JP, Gerdin B, Eriksson E. Cdc42 and p190RhoGAP activation by CCN2 regulates cell spreading and polarity and induces actin disassembly in migrating keratinocytes. Int Wound J. 2016 Jun; 13(3):372-81.
-
Kiwanuka E, Hackl F, Caterson EJ, Nowinski D, Junker JP, Gerdin B, Eriksson E. CCN2 is transiently expressed by keratinocytes during re-epithelialization and regulates keratinocyte migration in?vitro by the ras-MEK-ERK signaling pathway. J Surg Res. 2013 Dec; 185(2):e109-19.
-
McCormick BA. Using Salmonella enterica serotype typhimurium to model intestinal fibrosis. Gastroenterology. 2008 Mar; 134(3):872-5.
-
Arnott JA, Nuglozeh E, Rico MC, Arango-Hisijara I, Odgren PR, Safadi FF, Popoff SN. Connective tissue growth factor (CTGF/CCN2) is a downstream mediator for TGF-beta1-induced extracellular matrix production in osteoblasts. J Cell Physiol. 2007 Mar; 210(3):843-52.
-
Thannickal VJ, Flaherty KR, Martinez FJ, Lynch JP. Idiopathic pulmonary fibrosis: emerging concepts on pharmacotherapy. Expert Opin Pharmacother. 2004 Aug; 5(8):1671-86.
-
Safadi FF, Xu J, Smock SL, Kanaan RA, Selim AH, Odgren PR, Marks SC, Owen TA, Popoff SN. Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo. J Cell Physiol. 2003 Jul; 196(1):51-62.
-
Xu J, Smock SL, Safadi FF, Rosenzweig AB, Odgren PR, Marks SC, Owen TA, Popoff SN. Cloning the full-length cDNA for rat connective tissue growth factor: implications for skeletal development. J Cell Biochem. 2000 Feb; 77(1):103-15.