 Melatonin
"Melatonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
| Descriptor ID |
D008550
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| MeSH Number(s) |
D03.438.473.914.481 D06.472.506
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Melatonin".
Below are MeSH descriptors whose meaning is more specific than "Melatonin".
This graph shows the total number of publications written about "Melatonin" by people in this website by year, and whether "Melatonin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 0 | 1 | 1 | | 1983 | 1 | 0 | 1 | | 1984 | 1 | 2 | 3 | | 1985 | 3 | 0 | 3 | | 1986 | 2 | 0 | 2 | | 1987 | 1 | 1 | 2 | | 1988 | 2 | 0 | 2 | | 1989 | 2 | 1 | 3 | | 1990 | 2 | 1 | 3 | | 1991 | 1 | 2 | 3 | | 1993 | 2 | 0 | 2 | | 1994 | 1 | 0 | 1 | | 1995 | 3 | 0 | 3 | | 1996 | 3 | 1 | 4 | | 1997 | 5 | 0 | 5 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 2 | 0 | 2 |
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Below are the most recent publications written about "Melatonin" by people in Profiles.
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Loureiro R, Magalhães-Novais S, Mesquita KA, Baldeiras I, Sousa IS, Tavares LC, Barbosa IA, Oliveira PJ, Vega-Naredo I. Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget. 2015 Jul 10; 6(19):17081-96.
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Brown SB, Hankinson SE, Eliassen AH, Reeves KW, Qian J, Arcaro KF, Wegrzyn LR, Willett WC, Schernhammer ES. Urinary melatonin concentration and the risk of breast cancer in Nurses' Health Study II. Am J Epidemiol. 2015 Feb 1; 181(3):155-62.
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Green EA, Black BK, Biaggioni I, Paranjape SY, Bagai K, Shibao C, Okoye MC, Dupont WD, Robertson D, Raj SR. Melatonin reduces tachycardia in postural tachycardia syndrome: a randomized, crossover trial. Cardiovasc Ther. 2014 Jun; 32(3):105-12.
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Sturgeon SR, Doherty A, Reeves KW, Bigelow C, Stanczyk FZ, Ockene JK, Liu S, Manson JE, Neuhouser ML. Urinary levels of melatonin and risk of postmenopausal breast cancer: women's health initiative observational cohort. Cancer Epidemiol Biomarkers Prev. 2014 Apr; 23(4):629-37.
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Martins PN, Markmann JF. Age-related differences in hepatic ischemia/reperfusion: gene activation, liver injury, and protective effect of melatonin. J Surg Res. 2013 Nov; 185(1):e19-21.
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Helfer G, Ross AW, Russell L, Thomson LM, Shearer KD, Goodman TH, McCaffery PJ, Morgan PJ. Photoperiod regulates vitamin A and Wnt/ß-catenin signaling in F344 rats. Endocrinology. 2012 Feb; 153(2):815-24.
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Vega-Naredo I, Caballero B, Sierra V, García-Macia M, de Gonzalo-Calvo D, Oliveira PJ, Rodríguez-Colunga MJ, Coto-Montes A. Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity. J Pineal Res. 2012 Jan; 52(1):80-92.
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Paul MJ, Schwartz WJ. Circadian rhythms: how does a reindeer tell time? Curr Biol. 2010 Mar 23; 20(6):R280-2.
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Yasuo S, von Gall C, Weaver DR, Korf HW. Rhythmic expression of clock genes in the ependymal cell layer of the third ventricle of rodents is independent of melatonin signaling. Eur J Neurosci. 2008 Dec; 28(12):2443-50.
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von Gall C, Weaver DR. Loss of responsiveness to melatonin in the aging mouse suprachiasmatic nucleus. Neurobiol Aging. 2008 Mar; 29(3):464-70.
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