Serotonin

"Serotonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.

Descriptor ID	D012701
MeSH Number(s)	D02.092.211.215.801.852 D03.633.100.473.914.814 D23.469.050.650
Concept/Terms	Serotonin Serotonin 5-Hydroxytryptamine 5 Hydroxytryptamine Hippophaine 3-(2-Aminoethyl)-1H-indol-5-ol Enteramine 5-HT Hydroxytryptamine Hydroxytryptamine

Below are MeSH descriptors whose meaning is more general than "Serotonin".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amines [D02.092]
Biogenic Amines [D02.092.211]
Biogenic Monoamines [D02.092.211.215]
Tryptamines [D02.092.211.215.801]
Serotonin [D02.092.211.215.801.852]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Indoles [D03.633.100.473]
Tryptamines [D03.633.100.473.914]
Serotonin [D03.633.100.473.914.814]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Serotonin [D23.469.050.650]

Below are MeSH descriptors whose meaning is related to "Serotonin".

Below are MeSH descriptors whose meaning is more specific than "Serotonin".

Serotonin
5-Methoxytryptamine

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Serotonin" by people in this website by year, and whether "Serotonin" was a major or minor topic of these publications.

Bar chart showing 52 publications over 26 distinct years, with a maximum of 5 publications in 2006 and 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1998	1	0	1
2001	0	1	1
2002	0	2	2
2003	2	1	3
2004	1	2	3
2005	0	3	3
2006	2	3	5
2007	2	3	5
2008	0	1	1
2009	2	1	3
2010	0	1	1
2011	0	1	1
2012	1	1	2
2013	2	1	3
2015	0	1	1
2016	1	0	1
2017	2	1	3
2018	1	0	1
2019	1	1	2
2020	0	1	1
2021	1	1	2
2022	1	0	1
2023	2	0	2
2024	1	1	2

Below are the most recent publications written about "Serotonin" by people in Profiles.

Frelinger AL, Haynes RL, Goldstein RD, Berny-Lang MA, Gerrits AJ, Riehs M, Haas EA, Paunovic B, Mena OJ, Campman SC, Milne GL, Sleeper LA, Kinney HC, Michelson AD. Dysregulation of platelet serotonin, 14-3-3, and GPIX in sudden infant death syndrome. Sci Rep. 2024 05 15; 14(1):11092.

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Nakamura S, Sasaki T, Uenoyama Y, Inoue N, Nakanishi M, Yamada K, Morishima A, Suzumura R, Kitagawa Y, Morita Y, Ohkura S, Tsukamura H. Raphe glucose-sensing serotonergic neurons stimulate KNDy neurons to enhance LH pulses via 5HT2CR: rat and goat studies. Sci Rep. 2024 05 03; 14(1):10190.

View in: PubMed
Yemini E. Systems neuroscience: Foraging through serotonin's tangled web. Curr Biol. 2023 07 24; 33(14):R767-R770.

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Cheung A, Konno K, Imamura Y, Matsui A, Abe M, Sakimura K, Sasaoka T, Uemura T, Watanabe M, Futai K. Neurexins in serotonergic neurons regulate neuronal survival, serotonin transmission, and complex mouse behaviors. Elife. 2023 01 25; 12.

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Grech J, Chan MV, Ochin C, Lachapelle A, Thibord F, Schneider Z, Nkambule BB, Armstrong PCJ, de Melendez CW, Tucker KL, Garelnabi M, Warner TD, Chen MH, Johnson AD. Serotonin-Affecting Antidepressant Use in Relation to Platelet Reactivity. Clin Pharmacol Ther. 2022 04; 111(4):909-918.

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Maicas M, Jimeno-Mart?n ?, Mill?n-Trejo A, Alkema MJ, Flames N. The transcription factor LAG-1/CSL plays a Notch-independent role in controlling terminal differentiation, fate maintenance, and plasticity of serotonergic chemosensory neurons. PLoS Biol. 2021 07; 19(7):e3001334.

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Neculaes B, Frelinger AL, Gerrits AJ, Gremmel T, Forde EE, Klopman S, Carmichael SL, Michelson AD. Activation of platelet-rich plasma by pulse electric fields: Voltage, pulse width and calcium concentration can be used to control and tune the release of growth factors, serotonin and hemoglobin. PLoS One. 2021; 16(4):e0249209.

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Chen Z, Luo J, Li J, Kim G, Stewart A, Urban JF, Huang Y, Chen S, Wu LG, Chesler A, Trinchieri G, Li W, Wu C. Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis. Immunity. 2021 01 12; 54(1):151-163.e6.

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Yao J, Wang J, Wu L, Lu H, Wang Z, Yu P, Xiao H, Gao R, Yu J. Perinatal exposure to bisphenol A causes a disturbance of neurotransmitter metabolic pathways in female mouse offspring: A focus on the tryptophan and dopamine pathways. Chemosphere. 2020 Sep; 254:126715.

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Rodr?guez-Rodr?guez A, Shuvaev S, Rotile N, Jones CM, Probst CK, Dos Santos Ferreira D, Graham-O Regan K, Boros E, Knipe RS, Griffith JW, Tager AM, Bogdanov A, Caravan P. Peroxidase Sensitive Amplifiable Probe for Molecular Magnetic Resonance Imaging of Pulmonary Inflammation. ACS Sens. 2019 09 27; 4(9):2412-2419.

View in: PubMed

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