"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
|
| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 1 | 1 | 2 |
| 1995 | 1 | 0 | 1 |
| 1996 | 3 | 0 | 3 |
| 1997 | 0 | 1 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 2 | 2 | 4 |
| 2001 | 2 | 1 | 3 |
| 2002 | 3 | 2 | 5 |
| 2003 | 3 | 2 | 5 |
| 2004 | 4 | 0 | 4 |
| 2005 | 1 | 0 | 1 |
| 2006 | 6 | 1 | 7 |
| 2007 | 6 | 1 | 7 |
| 2008 | 3 | 1 | 4 |
| 2009 | 4 | 5 | 9 |
| 2010 | 9 | 2 | 11 |
| 2011 | 5 | 1 | 6 |
| 2012 | 6 | 2 | 8 |
| 2013 | 5 | 1 | 6 |
| 2014 | 2 | 3 | 5 |
| 2015 | 5 | 0 | 5 |
| 2016 | 1 | 1 | 2 |
| 2017 | 4 | 2 | 6 |
| 2018 | 0 | 1 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 2 | 4 |
| 2021 | 2 | 2 | 4 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Synapses" by people in Profiles.
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Donnard E, Shu H, Garber M. Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model. PLoS Genet. 2022 06; 18(6):e1010221.
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Manabe T, R?cz I, Schwartz S, Oberle L, Santarelli F, Emmrich JV, Neher JJ, Heneka MT. Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing. J Neurochem. 2021 11; 159(3):525-542.
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DeKorver NW, Chaudoin TR, Zhao G, Wang D, Arikkath J, Bonasera SJ. Complement Component C3 Loss leads to Locomotor Deficits and Altered Cerebellar Internal Granule Cell In Vitro Synaptic Protein Expression in C57BL/6 Mice. Mol Neurobiol. 2021 Nov; 58(11):5857-5875.
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Emmons SW, Yemini E, Zimmer M. Methods for analyzing neuronal structure and activity in Caenorhabditis elegans. Genetics. 2021 08 09; 218(4).
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Ackerman SD, Perez-Catalan NA, Freeman MR, Doe CQ. Astrocytes close a motor circuit critical period. Nature. 2021 04; 592(7854):414-420.
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Ding X, Wang J, Huang M, Chen Z, Liu J, Zhang Q, Zhang C, Xiang Y, Zen K, Li L. Loss of microglial SIRPa promotes synaptic pruning in preclinical models of neurodegeneration. Nat Commun. 2021 04 01; 12(1):2030.
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Uchigashima M, Konno K, Demchak E, Cheung A, Watanabe T, Keener DG, Abe M, Le T, Sakimura K, Sasaoka T, Uemura T, Imamura Kawasawa Y, Watanabe M, Futai K. Specific Neuroligin3-aNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus. Elife. 2020 12 23; 9.
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Chen J, Poskanzer KE, Freeman MR, Monk KR. Live-imaging of astrocyte morphogenesis and function in zebrafish neural circuits. Nat Neurosci. 2020 10; 23(10):1297-1306.
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Kamalova A, Futai K, Delpire E, Nakagawa T. AMPA Receptor Auxiliary Subunit GSG1L Suppresses Short-Term Facilitation in Corticothalamic Synapses and Determines Seizure Susceptibility. Cell Rep. 2020 07 21; 32(3):107921.
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Cook SJ, Crouse CM, Yemini E, Hall DH, Emmons SW, Hobert O. The connectome of the Caenorhabditis elegans pharynx. J Comp Neurol. 2020 11 01; 528(16):2767-2784.