"Immunological Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interfaces between T-CELLS and ANTIGEN-PRESENTING CELLS. Supramolecular organization of proteins takes place at these synapses involving various types of immune cells. Immunological synapses can have several functions including LYMPHOCYTE ACTIVATION; enhancing, balancing, or terminating signaling; or directing cytokine secretion.
| Descriptor ID |
D054992
|
| MeSH Number(s) |
A11.284.149.165.420.548 A15.382.370
|
| Concept/Terms |
Immunological Synapses- Immunological Synapses
- Immunological Synapse
- Synapse, Immunological
- Synapses, Immunological
|
Below are MeSH descriptors whose meaning is more general than "Immunological Synapses".
Below are MeSH descriptors whose meaning is more specific than "Immunological Synapses".
This graph shows the total number of publications written about "Immunological Synapses" by people in this website by year, and whether "Immunological Synapses" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 2 | 1 | 3 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunological Synapses" by people in Profiles.
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Junqueira C, Polidoro RB, Castro G, Absalon S, Liang Z, Sen Santara S, Crespo ?, Pereira DB, Gazzinelli RT, Dvorin JD, Lieberman J. ?d T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis. Nat Immunol. 2021 03; 22(3):347-357.
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Shea-Donohue T, Urban JF. Neuroimmune Modulation of Gut Function. Handb Exp Pharmacol. 2017; 239:247-267.
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Vivar OI, Masi G, Carpier JM, Magalhaes JG, Galgano D, Pazour GJ, Amigorena S, Hivroz C, Baldari CT. IFT20 controls LAT recruitment to the immune synapse and T-cell activation in vivo. Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2):386-91.
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Vertii A, Zimmerman W, Ivshina M, Doxsey S. Centrosome-intrinsic mechanisms modulate centrosome integrity during fever. Mol Biol Cell. 2015 Oct 01; 26(19):3451-63.
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Finetti F, Patrussi L, Galgano D, Cassioli C, Perinetti G, Pazour GJ, Baldari CT. The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse. J Cell Sci. 2015 Jul 15; 128(14):2541-52.
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Hsu CJ, Hsieh WT, Waldman A, Clarke F, Huseby ES, Burkhardt JK, Baumgart T. Ligand mobility modulates immunological synapse formation and T cell activation. PLoS One. 2012; 7(2):e32398.
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Friedman RS, Beemiller P, Sorensen CM, Jacobelli J, Krummel MF. Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics. J Exp Med. 2010 Nov 22; 207(12):2733-49.
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Finetti F, Paccani SR, Riparbelli MG, Giacomello E, Perinetti G, Pazour GJ, Rosenbaum JL, Baldari CT. Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse. Nat Cell Biol. 2009 Nov; 11(11):1332-9.