Fanconi Anemia Complementation Group D2 Protein
"Fanconi Anemia Complementation Group D2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.
| Descriptor ID |
D052236
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| MeSH Number(s) |
D12.776.313.812 D12.776.660.285 D12.776.744.484
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fanconi Anemia Complementation Group D2 Protein".
Below are MeSH descriptors whose meaning is more specific than "Fanconi Anemia Complementation Group D2 Protein".
This graph shows the total number of publications written about "Fanconi Anemia Complementation Group D2 Protein" by people in this website by year, and whether "Fanconi Anemia Complementation Group D2 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fanconi Anemia Complementation Group D2 Protein" by people in Profiles.
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Suzuki S, Racine RR, Manalo NA, Cantor SB, Raffel GD. Impairment of fetal hematopoietic stem cell function in the absence of Fancd2. Exp Hematol. 2017 04; 48:79-86.
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Ramirez YP, Mladek AC, Phillips RM, Gynther M, Rautio J, Ross AH, Wheelhouse RT, Sakaria JN. Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth. Mol Cancer Ther. 2015 Jan; 14(1):111-9.
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Peng M, Xie J, Ucher A, Stavnezer J, Cantor SB. Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses. EMBO J. 2014 Aug 01; 33(15):1698-712.
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Peng M, Litman R, Xie J, Sharma S, Brosh RM, Cantor SB. The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells. EMBO J. 2007 Jul 11; 26(13):3238-49.
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Pejovic T, Yates JE, Liu HY, Hays LE, Akkari Y, Torimaru Y, Keeble W, Rathbun RK, Rodgers WH, Bale AE, Ameziane N, Zwaan CM, Errami A, Thuillier P, Cappuccini F, Olson SB, Cain JM, Bagby GC. Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer. Cancer Res. 2006 Sep 15; 66(18):9017-25.
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Houghtaling S, Timmers C, Noll M, Finegold MJ, Jones SN, Meyn MS, Grompe M. Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice. Genes Dev. 2003 Aug 15; 17(16):2021-35.