Fanconi Anemia Complementation Group A Protein
"Fanconi Anemia Complementation Group A Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Fanconi anemia complementation group protein that is the most commonly mutated protein in FANCONI ANEMIA. It undergoes PHOSPHORYLATION by PROTEIN KINASE B and forms a complex with FANCC PROTEIN in the CELL NUCLEUS.
| Descriptor ID |
D052217
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| MeSH Number(s) |
D12.776.313.500 D12.776.660.264 D12.776.744.476
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fanconi Anemia Complementation Group A Protein".
Below are MeSH descriptors whose meaning is more specific than "Fanconi Anemia Complementation Group A Protein".
This graph shows the total number of publications written about "Fanconi Anemia Complementation Group A Protein" by people in this website by year, and whether "Fanconi Anemia Complementation Group A Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "Fanconi Anemia Complementation Group A Protein" by people in Profiles.
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Haworth KG, Ironside C, Ramirez MA, Weitz S, Beard BC, Schwartz JD, Adair JE, Kiem HP. Minimal conditioning in Fanconi anemia promotes multi-lineage marrow engraftment at 10-fold lower cell doses. J Gene Med. 2018 10; 20(10-11):e3050.
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Adair JE, Chandrasekaran D, Sghia-Hughes G, Haworth KG, Woolfrey AE, Burroughs LM, Choi GY, Becker PS, Kiem HP. Novel lineage depletion preserves autologous blood stem cells for gene therapy of Fanconi anemia complementation group A. Haematologica. 2018 11; 103(11):1806-1814.
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Peng M, Xie J, Ucher A, Stavnezer J, Cantor SB. Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses. EMBO J. 2014 Aug 01; 33(15):1698-712.
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Becker PS, Taylor JA, Trobridge GD, Zhao X, Beard BC, Chien S, Adair J, Kohn DB, Wagner JE, Shimamura A, Kiem HP. Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector. Gene Ther. 2010 Oct; 17(10):1244-52.