"Chymotrypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
| Descriptor ID |
D002918
|
| MeSH Number(s) |
D08.811.277.656.300.760.176 D08.811.277.656.959.350.176
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Chymotrypsin".
Below are MeSH descriptors whose meaning is more specific than "Chymotrypsin".
This graph shows the total number of publications written about "Chymotrypsin" by people in this website by year, and whether "Chymotrypsin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 4 | 0 | 4 |
| 2005 | 4 | 0 | 4 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Chymotrypsin" by people in Profiles.
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Yu Y, Wagner EK, Souied EH, Seitsonen S, Immonen IJ, H?pp?l? P, Raychaudhuri S, Daly MJ, Seddon JM. Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degeneration?. Hum Mol Genet. 2016 12 01; 25(23):5276-5285.
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Lee H, Tang LH, Veras EF, Klimstra DS. The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases. Am J Surg Pathol. 2012 Mar; 36(3):402-8.
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Jordan BJ, Hong R, Han G, Rana S, Rotello VM. Modulation of enzyme-substrate selectivity using tetraethylene glycol functionalized gold nanoparticles. Nanotechnology. 2009 Oct 28; 20(43):434004.
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Ghosh KK, Verma SK. Kinetics of alpha-chymotrypsin catalyzed hydrolysis of 4-nitrophenyl acetate in ethanolamine surfactants. Indian J Biochem Biophys. 2008 Oct; 45(5):350-3.
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You CC, Agasti SS, Rotello VM. Isomeric control of protein recognition with amino acid- and dipeptide-functionalized gold nanoparticles. Chemistry. 2008; 14(1):143-50.
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De M, You CC, Srivastava S, Rotello VM. Biomimetic interactions of proteins with functionalized nanoparticles: a thermodynamic study. J Am Chem Soc. 2007 Sep 05; 129(35):10747-53.
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Elias RJ, Bridgewater JD, Vachet RW, Waraho T, McClements DJ, Decker EA. Antioxidant mechanisms of enzymatic hydrolysates of beta-lactoglobulin in food lipid dispersions. J Agric Food Chem. 2006 Dec 13; 54(25):9565-72.
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You CC, Agasti SS, De M, Knapp MJ, Rotello VM. Modulation of the catalytic behavior of alpha-chymotrypsin at monolayer-protected nanoparticle surfaces. J Am Chem Soc. 2006 Nov 15; 128(45):14612-8.
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You CC, Arvizo RR, Rotello VM. Regulation of alpha-chymotrypsin activity on the surface of substrate-functionalized gold nanoparticles. Chem Commun (Camb). 2006 Jul 21; (27):2905-7.
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You CC, De M, Rotello VM. Contrasting effects of exterior and interior hydrophobic moieties in the complexation of amino acid functionalized gold clusters with alpha-chymotrypsin. Org Lett. 2005 Dec 08; 7(25):5685-8.