Reverse Transcriptase Polymerase Chain Reaction

"Reverse Transcriptase Polymerase Chain Reaction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.

Descriptor ID	D020133
MeSH Number(s)	E05.393.620.500.725
Concept/Terms	Reverse Transcriptase Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Polymerase Chain Reaction, Reverse Transcriptase Reverse Transcriptase PCR PCR, Reverse Transcriptase Transcriptase PCR, Reverse

Below are MeSH descriptors whose meaning is more general than "Reverse Transcriptase Polymerase Chain Reaction".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Nucleic Acid Amplification Techniques [E05.393.620]
Polymerase Chain Reaction [E05.393.620.500]
Reverse Transcriptase Polymerase Chain Reaction [E05.393.620.500.725]

Below are MeSH descriptors whose meaning is related to "Reverse Transcriptase Polymerase Chain Reaction".

Below are MeSH descriptors whose meaning is more specific than "Reverse Transcriptase Polymerase Chain Reaction".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Reverse Transcriptase Polymerase Chain Reaction" by people in this website by year, and whether "Reverse Transcriptase Polymerase Chain Reaction" was a major or minor topic of these publications.

Bar chart showing 434 publications over 24 distinct years, with a maximum of 40 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	1	2
1999	0	13	13
2000	0	11	11
2001	0	16	16
2002	1	22	23
2003	0	27	27
2004	1	31	32
2005	0	36	36
2006	1	24	25
2007	1	27	28
2008	1	27	28
2009	2	28	30
2010	1	39	40
2011	0	27	27
2012	0	16	16
2013	1	16	17
2014	0	25	25
2015	0	13	13
2016	1	10	11
2017	0	2	2
2019	0	2	2
2020	2	4	6
2021	0	3	3
2022	0	1	1

Below are the most recent publications written about "Reverse Transcriptase Polymerase Chain Reaction" by people in Profiles.

Krasemann S, Haferkamp U, Pfefferle S, Woo MS, Heinrich F, Schweizer M, Appelt-Menzel A, Cubukova A, Barenberg J, Leu J, Hartmann K, Thies E, Littau JL, Sepulveda-Falla D, Zhang L, Ton K, Liang Y, Matschke J, Ricklefs F, Sauvigny T, Sperhake J, Fitzek A, Gerhartl A, Brachner A, Geiger N, König EM, Bodem J, Franzenburg S, Franke A, Moese S, Müller FJ, Geisslinger G, Claussen C, Kannt A, Zaliani A, Gribbon P, Ondruschka B, Neuhaus W, Friese MA, Glatzel M, Pless O. The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2. Stem Cell Reports. 2022 02 08; 17(2):307-320.

View in: PubMed
Sirikajornpan K, Suntarattiwong P, Suwanpakdee D, Tabprasit S, Buddhari D, Thaisomboonsuk B, Klungthong C, Poolpanichupatam Y, Buathong R, Srikiatkhachorn A, Jones A, Fernandez S, Hunsawong T. Standardization and Evaluation of an Anti-ZIKV IgM ELISA Assay for the Serological Diagnosis of Zika Virus Infection. Am J Trop Med Hyg. 2021 08 02; 105(4):936-941.

View in: PubMed
Nörz D, Pfefferle S, Grunwald M, Fischer N, Aepfelbacher M, Lütgehetmann M. Modifying a Diagnostic SARS-CoV-2 Spike PCR to Turn a Del69/70 Dropout into a Discriminatory On-Target Assay. J Mol Diagn. 2021 06; 23(6):777-778.

View in: PubMed
Nörz D, Hoffmann A, Aepfelbacher M, Pfefferle S, Lütgehetmann M. Clinical evaluation of a fully automated, laboratory-developed multiplex RT-PCR assay integrating dual-target SARS-CoV-2 and influenza A/B detection on a high-throughput platform. J Med Microbiol. 2021 Feb; 70(2).

View in: PubMed
Ghandili S, Pfefferle S, Roedl K, Sonnemann P, Karagiannis P, Boenisch O, Kluge S, Schmiedel S, Ittrich H, Rohde H, Lütgehetmann M, Weisel K, Bokemeyer C, Wichmann D, Fiedler W, Jarczak D, Modemann F. Challenges in treatment of patients with acute leukemia and COVID-19: a series of 12 patients. Blood Adv. 2020 12 08; 4(23):5936-5941.

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Aguilar R, Bustos FJ, Nardocci G, van Zundert B, Montecino M. Epigenetic silencing of the osteoblast-lineage gene program during hippocampal maturation. J Cell Biochem. 2021 04; 122(3-4):367-384.

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Rogers AA, Baumann RE, Borillo GA, Kagan RM, Batterman HJ, Galdzicka MM, Marlowe EM. Evaluation of Transport Media and Specimen Transport Conditions for the Detection of SARS-CoV-2 by Use of Real-Time Reverse Transcription-PCR. J Clin Microbiol. 2020 Jul 23; 58(8).

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Pederson T. The 50th anniversary of reverse transcriptase-and its ironic legacy in the time of coronavirus. FASEB J. 2020 06; 34(6):7219-7221.

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Nörz D, Fischer N, Schultze A, Kluge S, Mayer-Runge U, Aepfelbacher M, Pfefferle S, Lütgehetmann M. Clinical evaluation of a SARS-CoV-2 RT-PCR assay on a fully automated system for rapid on-demand testing in the hospital setting. J Clin Virol. 2020 07; 128:104390.

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Pfefferle S, Reucher S, Nörz D, Lütgehetmann M. Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system. Euro Surveill. 2020 03; 25(9).

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