"Protamines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
| Descriptor ID |
D011479
|
| MeSH Number(s) |
D12.776.660.750 D12.776.664.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protamines".
Below are MeSH descriptors whose meaning is more specific than "Protamines".
This graph shows the total number of publications written about "Protamines" by people in this website by year, and whether "Protamines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Protamines" by people in Profiles.
-
Chen Q, Huang L, Pan D, Zhu LJ, Wang YX. Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis. Cell Rep. 2018 03 13; 22(11):2860-2872.
-
Yassine S, Escoffier J, Martinez G, Coutton C, Karaouz?ne T, Zouari R, Ravanat JL, Metzler-Guillemain C, Lee HC, Fissore R, Hennebicq S, Ray PF, Arnoult C. Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development. Mol Hum Reprod. 2015 Feb; 21(2):169-85.
-
Stone DH, Nolan BW, Schanzer A, Goodney PP, Cambria RA, Likosky DS, Walsh DB, Cronenwett JL. Protamine reduces bleeding complications associated with carotid endarterectomy without increasing the risk of stroke. J Vasc Surg. 2010 Mar; 51(3):559-64, 564.e1.
-
Upchurch GR, Welch GN, Freedman JE, Fabian AJ, Pigazzi A, Scribner AM, Alpert CS, Keaney JF, Loscalzo J. High-dose heparin decreases nitric oxide production by cultured bovine endothelial cells. Circulation. 1997 Apr 15; 95(8):2115-21.
-
Connelly NR, Kiessling BM, Brull SJ. Does tranexamic acid decrease bleeding in patients undergoing cardiopulmonary bypass? Yale J Biol Med. 1994 Sep-Dec; 67(5-6):265-8.
-
Jones DR, Hill RC, Vasilakis A, Hollingsed MJ, Graeber GM, Gustafson RA, Cruzzavala JL, Murray GF. Safe use of heparin-coated bypass circuits incorporating a pump-oxygenator. Ann Thorac Surg. 1994 Apr; 57(4):815-8; discussion 818-9.
-
Jones DR, Hill RC, Hollingsed MJ, Stullken E, Graeber GM, Gustafson RA, Murray GF. Use of heparin-coated cardiopulmonary bypass. Ann Thorac Surg. 1993 Sep; 56(3):566-8.