GATA3 Transcription Factor

"GATA3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A GATA transcription factor that is found predominately in LYMPHOID CELL precursors and has been implicated in the CELL DIFFERENTIATION of HELPER T-CELLS. Haploinsufficiency of GATA3 is associated with HYPOPARATHYROIDISM; SENSORINEURAL HEARING LOSS; and renal anomalies syndrome.

Descriptor ID	D050990
MeSH Number(s)	D12.776.260.235.687 D12.776.260.257.300 D12.776.930.216.687 D12.776.930.314.300
Concept/Terms	GATA3 Transcription Factor GATA3 Transcription Factor Transcription Factor, GATA3 Transcription Factor GATA3 GATA3, Transcription Factor Nuclear Factor-Erythroid 1C Nuclear Factor Erythroid 1C GATA-3 Factors GATA 3 Factors NF-E1C Protein NF E1C Protein

Below are MeSH descriptors whose meaning is more general than "GATA3 Transcription Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Erythroid-Specific DNA-Binding Factors [D12.776.260.235]
GATA3 Transcription Factor [D12.776.260.235.687]
GATA Transcription Factors [D12.776.260.257]
GATA3 Transcription Factor [D12.776.260.257.300]
Transcription Factors [D12.776.930]
Erythroid-Specific DNA-Binding Factors [D12.776.930.216]
GATA3 Transcription Factor [D12.776.930.216.687]
GATA Transcription Factors [D12.776.930.314]
GATA3 Transcription Factor [D12.776.930.314.300]

Below are MeSH descriptors whose meaning is related to "GATA3 Transcription Factor".

Below are MeSH descriptors whose meaning is more specific than "GATA3 Transcription Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "GATA3 Transcription Factor" by people in this website by year, and whether "GATA3 Transcription Factor" was a major or minor topic of these publications.

Bar chart showing 8 publications over 7 distinct years, with a maximum of 2 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2002	0	1	1
2010	1	0	1
2012	1	1	2
2017	1	0	1
2019	0	1	1
2020	0	1	1

Below are the most recent publications written about "GATA3 Transcription Factor" by people in Profiles.

Muse ME, Titus AJ, Salas LA, Wilkins OM, Mullen C, Gregory KJ, Schneider SS, Crisi GM, Jawale RM, Otis CN, Christensen BC, Arcaro KF. Enrichment of CpG island shore region hypermethylation in epigenetic breast field cancerization. Epigenetics. 2020 10; 15(10):1093-1106.

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Gowthaman U, Chen JS, Zhang B, Flynn WF, Lu Y, Song W, Joseph J, Gertie JA, Xu L, Collet MA, Grassmann JDS, Simoneau T, Chiang D, Berin MC, Craft JE, Weinstein JS, Williams A, Eisenbarth SC. Identification of a T follicular helper cell subset that drives anaphylactic IgE. Science. 2019 08 30; 365(6456).

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Li Y, Guan X, Liu W, Chen HL, Truscott J, Beyatli S, Metwali A, Weiner GJ, Zavazava N, Blumberg RS, Urban JF, Blazar BR, Elliott DE, Ince MN. Helminth-Induced Production of TGF-? and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells. J Immunol. 2018 11 15; 201(10):2910-2922.

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Lorentsen KJ, Cho JJ, Luo X, Zuniga AN, Urban JF, Zhou L, Gharaibeh R, Jobin C, Kladde MP, Avram D. Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma. Nat Commun. 2018 04 26; 9(1):1679.

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Dorfman DM, Morgan EA, Pelton A, Unitt C. T-cell transcription factor GATA-3 is an immunophenotypic marker of acute leukemias with T-cell differentiation. Hum Pathol. 2017 07; 65:166-174.

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Rudra D, deRoos P, Chaudhry A, Niec RE, Arvey A, Samstein RM, Leslie C, Shaffer SA, Goodlett DR, Rudensky AY. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat Immunol. 2012 Oct; 13(10):1010-9.

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Libraty DH, M?kel? S, Vlk J, Hurme M, Vaheri A, Ennis FA, Mustonen J. The degree of leukocytosis and urine GATA-3 mRNA levels are risk factors for severe acute kidney injury in Puumala virus nephropathia epidemica. PLoS One. 2012; 7(4):e35402.

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Yagi R, Junttila IS, Wei G, Urban JF, Zhao K, Paul WE, Zhu J. The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma. Immunity. 2010 Apr 23; 32(4):507-17.

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Yan W, Cao QJ, Arenas RB, Bentley B, Shao R. GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition. J Biol Chem. 2010 Apr 30; 285(18):14042-51.

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Morales-Tirado V, Sojka DK, Katzman SD, Lazarski CA, Finkelman FD, Urban JF, Fowell DJ. Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function. Blood. 2010 Apr 29; 115(17):3498-507.

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