"VDJ Recombinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recombinases involved in the rearrangement of immunity-related GENES such as IMMUNOGLOBULIN GENES and T-CELL RECEPTOR GENES.
Descriptor ID |
D045567
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MeSH Number(s) |
D08.811.739.900 D08.811.913.696.445.950
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Concept/Terms |
VDJ Recombinases- VDJ Recombinases
- V-(D)-J Recombinase
- VDJ Recombinase
- Recombinase, VDJ
- V(D)J Recombinase
- V-D-J Recombinase
- Recombinase, V-D-J
- V D J Recombinase
Immunoglobulin Recombinases- Immunoglobulin Recombinases
- Recombinases, Immunoglobulin
- Immunoglobulin Recombinase
- Recombinase, Immunoglobulin
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Below are MeSH descriptors whose meaning is more general than "VDJ Recombinases".
Below are MeSH descriptors whose meaning is more specific than "VDJ Recombinases".
This graph shows the total number of publications written about "VDJ Recombinases" by people in this website by year, and whether "VDJ Recombinases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
2004 | 3 | 0 | 3 |
2005 | 2 | 0 | 2 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "VDJ Recombinases" by people in Profiles.
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Carmona LM, Schatz DG. New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination. FEBS J. 2017 06; 284(11):1590-1605.
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Pilbeam K, Basse P, Brossay L, Vujanovic N, Gerstein R, Vallejo AN, Borghesi L. The ontogeny and fate of NK cells marked by permanent DNA rearrangements. J Immunol. 2008 Feb 01; 180(3):1432-41.
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Kuo YH, Gerstein RM, Castilla LH. Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development. Blood. 2008 Feb 01; 111(3):1543-51.
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Borghesi L, Aites J, Nelson S, Lefterov P, James P, Gerstein R. E47 is required for V(D)J recombinase activity in common lymphoid progenitors. J Exp Med. 2005 Dec 19; 202(12):1669-77.
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Labrie JE, Borghesi L, Gerstein RM. Bone marrow microenvironmental changes in aged mice compromise V(D)J recombinase activity and B cell generation. Semin Immunol. 2005 Oct; 17(5):347-55.
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Labrie JE, Sah AP, Allman DM, Cancro MP, Gerstein RM. Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice. J Exp Med. 2004 Aug 16; 200(4):411-23.
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Borghesi L, Gerstein RM. Developmental separation of V(D)J recombinase expression and initiation of IgH recombination in B lineage progenitors in vivo. J Exp Med. 2004 Feb 16; 199(4):483-9.
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Borghesi L, Hsu LY, Miller JP, Anderson M, Herzenberg L, Herzenberg L, Schlissel MS, Allman D, Gerstein RM. B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors. J Exp Med. 2004 Feb 16; 199(4):491-502.
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Kuhn-Hallek I, Sage DR, Stein L, Groelle H, Fingeroth JD. Expression of recombination activating genes (RAG-1 and RAG-2) in Epstein-Barr virus-bearing B cells. Blood. 1995 Mar 01; 85(5):1289-99.