"Receptor, trkB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.
| Descriptor ID |
D020813
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.700 D12.776.543.750.630.498 D12.776.543.750.750.400.550.600
|
| Concept/Terms |
Receptor, trkB- Receptor, trkB
- BDNF Receptor
- Receptor, BDNF
- trkB Receptor
- Receptor, Neurotrophic Tyrosine Kinase Type 2
- NTRK2 Receptor
- Receptor, NTRK2
- Brain Derived Neurotrophic Factor Receptor
- Neurotrophic Tyrosine Kinase Receptor Type 2
- trkB(gp145) Protein
- Neurotrophic Factor, Brain-Derived, Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, trkB".
Below are MeSH descriptors whose meaning is more specific than "Receptor, trkB".
This graph shows the total number of publications written about "Receptor, trkB" by people in this website by year, and whether "Receptor, trkB" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, trkB" by people in Profiles.
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Kempfle JS, Nguyen K, Hamadani C, Koen N, Edge AS, Kashemirov BA, Jung DH, McKenna CE. Bisphosphonate-Linked TrkB Agonist: Cochlea-Targeted Delivery of a Neurotrophic Agent as a Strategy for the Treatment of Hearing Loss. Bioconjug Chem. 2018 04 18; 29(4):1240-1250.
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Cordeira JW, Frank L, Sena-Esteves M, Pothos EN, Rios M. Brain-derived neurotrophic factor regulates hedonic feeding by acting on the mesolimbic dopamine system. J Neurosci. 2010 Feb 17; 30(7):2533-41.
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Unger TJ, Calderon GA, Bradley LC, Sena-Esteves M, Rios M. Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. J Neurosci. 2007 Dec 26; 27(52):14265-74.
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Merdek KD, Yang X, Taglienti CA, Shaw LM, Mercurio AM. Intrinsic signaling functions of the beta4 integrin intracellular domain. J Biol Chem. 2007 Oct 12; 282(41):30322-30.
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Carrasco MA, Castro PA, Sepulveda FJ, Cuevas M, Tapia JC, Izaurieta P, van Zundert B, Aguayo LG. Anti-homeostatic synaptic plasticity of glycine receptor function after chronic strychnine in developing cultured mouse spinal neurons. J Neurochem. 2007 Mar; 100(5):1143-54.
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Li HS, Xu XZ, Montell C. Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. Neuron. 1999 Sep; 24(1):261-73.