"Podocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly differentiated epithelial cells of the visceral layer of BOWMAN CAPSULE of the KIDNEY. They are composed of a cell body with major CELL SURFACE EXTENSIONS and secondary fingerlike extensions called pedicels. They enwrap the KIDNEY GLOMERULUS capillaries with their cell surface extensions forming a filtration structure. The pedicels of neighboring podocytes interdigitate with each other leaving between them filtration slits that are bridged by an extracellular structure impermeable to large macromolecules called the slit diaphragm, and provide the last barrier to protein loss in the KIDNEY.
Descriptor ID |
D050199
|
MeSH Number(s) |
A05.810.453.324.359.372.650 A05.810.453.736.520.720 A11.436.720
|
Concept/Terms |
Podocytes- Podocytes
- Podocyte
- Glomerular Visceral Epithelial Cells
- Visceral Epithelial Cells, Glomerular
- Epithelial Cells, Glomerular Visceral
|
Below are MeSH descriptors whose meaning is more general than "Podocytes".
Below are MeSH descriptors whose meaning is more specific than "Podocytes".
This graph shows the total number of publications written about "Podocytes" by people in this website by year, and whether "Podocytes" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 0 | 1 | 1 |
2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Podocytes" by people in Profiles.
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Pandit AP, Rennke HG, Denker BM. Podocytic Infolding Glomerulopathy in a Patient with Phospholipase A2 Receptor-Positive Membranous Nephropathy and Review of the Literature. Nephron. 2021; 145(5):496-502.
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Chen DP, Zaky ZS, Schold JD, Herlitz LC, El-Rifai R, Drawz PE, Bruggeman LA, Barisoni L, Hogan SL, Hu Y, O'Toole JF, Poggio ED, Sedor JR. Podocyte density is reduced in kidney allografts with high-risk APOL1 genotypes at transplantation. Clin Transplant. 2021 04; 35(4):e14234.
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Lamphier M, Zheng W, Latz E, Spyvee M, Hansen H, Rose J, Genest M, Yang H, Shaffer C, Zhao Y, Shen Y, Liu C, Liu D, Mempel TR, Rowbottom C, Chow J, Twine NC, Yu M, Gusovsky F, Ishizaka ST. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar; 85(3):429-40.
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Alexander JJ, Hack BK, Jacob A, Chang A, Haas M, Finberg RW, Quigg RJ. Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes. J Immunol. 2010 Sep 15; 185(6):3759-67.