Lupus Erythematosus, Systemic

"Lupus Erythematosus, Systemic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Descriptor ID	D008180
MeSH Number(s)	C17.300.480 C20.111.590
Concept/Terms	Lupus Erythematosus, Systemic Lupus Erythematosus, Systemic Systemic Lupus Erythematosus Lupus Erythematosus Disseminatus Libman-Sacks Disease Libman-Sacks Disease Disease, Libman-Sacks Libman Sacks Disease

Below are MeSH descriptors whose meaning is more general than "Lupus Erythematosus, Systemic".

Diseases [C]
Skin and Connective Tissue Diseases [C17]
Connective Tissue Diseases [C17.300]
Lupus Erythematosus, Systemic [C17.300.480]
Immune System Diseases [C20]
Autoimmune Diseases [C20.111]
Lupus Erythematosus, Systemic [C20.111.590]

Below are MeSH descriptors whose meaning is related to "Lupus Erythematosus, Systemic".

Below are MeSH descriptors whose meaning is more specific than "Lupus Erythematosus, Systemic".

Lupus Erythematosus, Systemic
Lupus Nephritis
Lupus Vasculitis, Central Nervous System

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lupus Erythematosus, Systemic" by people in this website by year, and whether "Lupus Erythematosus, Systemic" was a major or minor topic of these publications.

Bar chart showing 98 publications over 28 distinct years, with a maximum of 6 publications in 2018 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	2	3
1994	2	1	3
1995	4	1	5
1996	1	0	1
1997	1	0	1
1998	0	1	1
1999	2	1	3
2002	2	2	4
2003	3	0	3
2004	4	0	4
2005	4	0	4
2006	4	1	5
2007	4	0	4
2008	1	0	1
2009	3	0	3
2010	2	1	3
2011	3	1	4
2012	3	1	4
2013	3	2	5
2014	4	0	4
2015	2	2	4
2016	3	1	4
2017	1	3	4
2018	6	0	6
2019	4	0	4
2020	4	0	4
2021	6	0	6
2022	1	0	1

Below are the most recent publications written about "Lupus Erythematosus, Systemic" by people in Profiles.

Gkrouzman E, Peng M, Davis-Porada J, Kirou KA. Venous Thromboembolic Events in African American Lupus Patients in Association With Antiphospholipid Antibodies Compared to White Patients. Arthritis Care Res (Hoboken). 2022 04; 74(4):656-664.

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Lertratanakul A, Sun J, Wu PW, Lee J, Dyer A, Pearce W, McPherson D, Sutton-Tyrrell K, Thompson T, Barinas-Mitchell E, Ramsey-Goldman R. Risk factors for changes in carotid intima media thickness and plaque over 5 years in women with systemic lupus erythematosus. Lupus Sci Med. 2021 12; 8(1).

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Chew C, Reynolds JA, Lertratanakul A, Wu P, Urowitz M, Gladman DD, Fortin PR, Bae SC, Gordon C, Clarke AE, Bernatsky S, Hanly JG, Isenberg D, Rahman A, Sanchez-Guerrero J, Romero-Diaz J, Merrill J, Wallace D, Ginzler E, Khamashta M, Nived O, Jönsen A, Steinsson K, Manzi S, Kalunian K, Dooley MA, Petri M, Aranow C, van Vollenhoven R, Stoll T, Alarcón GS, Lim SS, Ruiz-Irastorza G, Peschken CA, Askanase AD, Kamen DL, ?nanç M, Ramsey-Goldman R, Bruce IN. Lower vitamin D is associated with metabolic syndrome and insulin resistance in systemic lupus: data from an international inception cohort. Rheumatology (Oxford). 2021 10 02; 60(10):4737-4747.

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Gallucci S, Meka S, Gamero AM. Abnormalities of the type I interferon signaling pathway in lupus autoimmunity. Cytokine. 2021 10; 146:155633.

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Moore E, Reynolds JA, Davidson A, Gallucci S, Morel L, Rao DA, Young HA, Putterman C. Promise and complexity of lupus mouse models. Nat Immunol. 2021 06; 22(6):683-686.

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Stearrett N, Dawson T, Rahnavard A, Bachali P, Bendall ML, Zeng C, Caricchio R, Pérez-Losada M, Grammer AC, Lipsky PE, Crandall KA. Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene Expression. Front Immunol. 2021; 12:661437.

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Motwani M, McGowan J, Antonovitch J, Gao KM, Jiang Z, Sharma S, Baltus GA, Nickerson KM, Marshak-Rothstein A, Fitzgerald KA. cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE. Front Immunol. 2021; 12:605930.

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Pachucki RJ, Corradetti C, Kohler L, Ghadiali J, Gallo PM, Nicastro L, Tursi SA, Gallucci S, Tükel Ç, Caricchio R. Persistent Bacteriuria and Antibodies Recognizing Curli/eDNA Complexes From Escherichia coli Are Linked to Flares in Systemic Lupus Erythematosus. Arthritis Rheumatol. 2020 11; 72(11):1872-1881.

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Nehar-Belaid D, Hong S, Marches R, Chen G, Bolisetty M, Baisch J, Walters L, Punaro M, Rossi RJ, Chung CH, Huynh RP, Singh P, Flynn WF, Tabanor-Gayle JA, Kuchipudi N, Mejias A, Collet MA, Lucido AL, Palucka K, Robson P, Lakshminarayanan S, Ramilo O, Wright T, Pascual V, Banchereau JF. Mapping systemic lupus erythematosus heterogeneity at the single-cell level. Nat Immunol. 2020 09; 21(9):1094-1106.

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Chodisetti SB, Fike AJ, Domeier PP, Schell SL, Mockus TE, Choi NM, Corradetti C, Hou B, Atkins HM, Caricchio R, Decker T, Lukacher AE, Olsen N, Rahman ZSM. Serine Phosphorylation of the STAT1 Transactivation Domain Promotes Autoreactive B Cell and Systemic Autoimmunity Development. J Immunol. 2020 05 15; 204(10):2641-2650.

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