DNA, Single-Stranded

"DNA, Single-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A single chain of deoxyribonucleotides that occurs in some bacteria and viruses. It usually exists as a covalently closed circle.

Descriptor ID	D004277
MeSH Number(s)	D13.444.308.497 G02.111.570.820.486.437 G05.360.580.437
Concept/Terms	DNA, Single-Stranded DNA, Single-Stranded DNA, Single Stranded Single-Stranded DNA Single Stranded DNA

Below are MeSH descriptors whose meaning is more general than "DNA, Single-Stranded".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
DNA [D13.444.308]
DNA, Single-Stranded [D13.444.308.497]
Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Nucleic Acid Conformation [G02.111.570.820.486]
DNA, Single-Stranded [G02.111.570.820.486.437]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Nucleic Acid Conformation [G05.360.580]
DNA, Single-Stranded [G05.360.580.437]

Below are MeSH descriptors whose meaning is more specific than "DNA, Single-Stranded".

DNA, Single-Stranded
DNA, Complementary

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA, Single-Stranded" by people in this website by year, and whether "DNA, Single-Stranded" was a major or minor topic of these publications.

Bar chart showing 67 publications over 29 distinct years, with a maximum of 6 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1996	2	0	2
1997	1	1	2
1998	0	2	2
1999	0	1	1
2000	1	0	1
2002	0	1	1
2003	0	1	1
2004	0	3	3
2005	1	2	3
2006	0	2	2
2007	0	1	1
2008	1	1	2
2009	0	2	2
2011	2	0	2
2012	0	1	1
2013	1	2	3
2014	3	1	4
2015	1	2	3
2016	0	1	1
2017	2	1	3
2018	5	0	5
2019	3	1	4
2020	1	2	3
2021	3	3	6
2022	1	2	3
2023	1	1	2
2024	1	1	2
2025	1	0	1

Below are the most recent publications written about "DNA, Single-Stranded" by people in Profiles.

Jordano-Raya M, Schrader CE, Ariza RR, Rold?n-Arjona T, C?rdoba-Ca?ero D. Divergent evolution of opposite base specificity and single-stranded DNA activity in animal and plant AP endonucleases. Nucleic Acids Res. 2025 Jan 07; 53(1).

View in: PubMed
Ogdahl JL, Chien P. Allosteric modulation of the Lon protease via ssDNA binding and local charge changes. J Biol Chem. 2025 Jan; 301(1):107993.

View in: PubMed
Sandler SJ, Bonde NJ, Wood EA, Cox MM, Keck JL. The intrinsically disordered linker in the single-stranded DNA-binding protein influences DNA replication restart and recombination pathways in Escherichia coli K-12. J Bacteriol. 2024 04 18; 206(4):e0033023.

View in: PubMed
Whalen JM, Cantor SB. Unveiling the toxicity of single-stranded DNA gaps through a yeast model. Nat Struct Mol Biol. 2023 07; 30(7):870-872.

View in: PubMed
Duckworth AT, Ducos PL, McMillan SD, Satyshur KA, Blumenthal KH, Deorio HR, Larson JA, Sandler SJ, Grant T, Keck JL. Replication fork binding triggers structural changes in the PriA helicase that govern DNA replication restart in E. coli. Nat Commun. 2023 05 11; 14(1):2725.

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Maiti A, Hedger AK, Myint W, Balachandran V, Watts JK, Schiffer CA, Matsuo H. Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state. Nat Commun. 2022 11 19; 13(1):7117.

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Iyer S, Mir A, Vega-Badillo J, Roscoe BP, Ibraheim R, Zhu LJ, Lee J, Liu P, Luk K, Mintzer E, Guo D, Soares de Brito J, Emerson CP, Zamore PD, Sontheimer EJ, Wolfe SA. Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors. CRISPR J. 2022 10; 5(5):685-701.

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Van Alstine S, Sandler SJ. Positive Charges Are Important for the SOS Constitutive Phenotype in recA730 and recA1202 Mutants of Escherichia coli K-12. J Bacteriol. 2022 05 17; 204(5):e0008122.

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Ghanta KS, Chen Z, Mir A, Dokshin GA, Krishnamurthy PM, Yoon Y, Gallant J, Xu P, Zhang XO, Ozturk AR, Shin M, Idrizi F, Liu P, Gneid H, Edraki A, Lawson ND, Rivera-P?rez JA, Sontheimer EJ, Watts JK, Mello CC. 5'-Modifications improve potency and efficacy of DNA donors for precision genome editing. Elife. 2021 10 19; 10.

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Paes Dias M, Tripathi V, van der Heijden I, Cong K, Manolika EM, Bhin J, Gogola E, Galanos P, Annunziato S, Lieftink C, And?jar-S?nchez M, Chakrabarty S, Smith GCM, van de Ven M, Beijersbergen RL, Bartkova J, Rottenberg S, Cantor S, Bartek J, Ray Chaudhuri A, Jonkers J. Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps. Mol Cell. 2021 11 18; 81(22):4692-4708.e9.

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