Immune Tolerance

"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.

Descriptor ID	D007108
MeSH Number(s)	G12.535.425
Concept/Terms	Immune Tolerance Immune Tolerance Tolerance, Immune Immunosuppression (Physiology) Immunosuppression (Physiology) Immunosuppressions (Physiology)

Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".

Biological Sciences [G]
Immune System Phenomena [G12]
Immunomodulation [G12.535]
Immune Tolerance [G12.535.425]

Below are MeSH descriptors whose meaning is related to "Immune Tolerance".

Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.

Bar chart showing 129 publications over 31 distinct years, with a maximum of 8 publications in 1999

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	2	2	4
1998	2	1	3
1999	7	1	8
2000	5	1	6
2001	4	0	4
2002	2	2	4
2003	2	4	6
2004	0	5	5
2005	3	3	6
2006	2	2	4
2007	3	1	4
2008	4	1	5
2009	5	2	7
2010	3	1	4
2011	2	2	4
2012	1	2	3
2013	3	4	7
2014	5	1	6
2015	2	0	2
2016	0	6	6
2017	1	0	1
2018	3	3	6
2019	1	3	4
2020	1	6	7
2021	2	0	2
2022	2	1	3
2023	0	1	1
2024	0	2	2
2025	1	1	2
2026	0	2	2

Below are the most recent publications written about "Immune Tolerance" by people in Profiles.

Frascoli M, Galván Peña S. Spatiotemporal dynamics of intestinal immune cells. Curr Opin Immunol. 2026 Oct; 102:102836.

View in: PubMed
Baeten P, Beets K, Schalley T, Verreycken J, Duran G, Lintsen D, Schuetz L, Zhong X, Nieuwschepen R, Schepers M, Moonen B, Bogie J, Van Broeckhoven J, Heirman C, Van den Heuvel J, Vanderborght B, Varela I, Nouille R, Jacobs L, Filtjens J, Kasmi S, Seynaeve E, Mavrovouna V, De Vrieze J, Brehm MA, Maréchal S, Janssens S, Lambolez F, Hellings N, De Koker S, Broux B. Autoantigen mRNA-LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity. Adv Sci (Weinh). 2026 Sep; 13(53):e76382.

View in: PubMed
Ardeshir A, O'Hagan D, Mehta I, Shandilya S, Hopkins LLJ, Adamson L, Kuroda MJ, Hahn PA, da Costa LAB, Fuchs SP, Martinez-Navio JM, Gardner MR, Van Rompay KKA, Magnani DM, Lifson JD, Gao G, Farzan M, Desrosiers RC, Das J, Martins MA. Determinants of successful AAV-vectored delivery of HIV-1 bNAbs in early life. Nature. 2025 09; 645(8082):1020-1028.

View in: PubMed
Zhou W, Zhou JZ, Ahmed A, Kim MJ, Guo CJ, Sonnenberg GF. ILC3s sense gut microbiota through STING to initiate immune tolerance. Immunity. 2025 Jul 08; 58(7):1762-1777.e7.

View in: PubMed
Chen JS, Lee D, Gowthaman U. T follicular helper cells in food allergy. Curr Opin Immunol. 2024 Dec; 91:102461.

View in: PubMed
Pitarresi JR, Fitzgerald KA. Unmasking immune suppression. Science. 2024 07 12; 385(6705):140-142.

View in: PubMed
Bertolini TB, Herzog RW, Kumar SRP, Sherman A, Rana J, Kaczmarek R, Yamada K, Arisa S, Lillicrap D, Terhorst C, Daniell H, Biswas M. Suppression of anti-drug antibody formation against coagulation factor VIII by oral delivery of anti-CD3 monoclonal antibody in hemophilia A mice. Cell Immunol. 2023 03; 385:104675.

View in: PubMed
Racine JJ, Morel L, Chen YG, Serreze DV. Editorial: Genetic basis of tolerance induction defects underlying the development of autoimmune pathologies. Front Immunol. 2022; 13:1069232.

View in: PubMed
Lyu M, Suzuki H, Kang L, Gaspal F, Zhou W, Goc J, Zhou L, Zhou J, Zhang W, Shen Z, Fox JG, Sockolow RE, Laufer TM, Fan Y, Eberl G, Withers DR, Sonnenberg GF. ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut. Nature. 2022 10; 610(7933):744-751.

View in: PubMed
Harkins AL, Kopec AL, Keeler AM. Regulatory T Cell Therapeutics for Neuroinflammatory Disorders. Crit Rev Immunol. 2022; 42(2):1-27.

View in: PubMed

People

Explore

Similar Concepts

Top Journals