"Genes, Immediate-Early" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters.
| Descriptor ID |
D017781
|
| MeSH Number(s) |
G05.360.340.024.340.330 G05.360.340.024.340.364.875.345 G05.360.340.358.024.875.345 G05.360.340.358.840.500.345
|
| Concept/Terms |
Genes, Immediate-Early- Genes, Immediate-Early
- Genes, Immediate Early
- Immediate-Early Genes
- Gene, Immediate-Early
- Immediate Early Genes
- Immediate-Early Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, Immediate-Early".
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Genome [G05.360.340]
- Genome Components [G05.360.340.024]
- Genes [G05.360.340.024.340]
- Genes, Immediate-Early [G05.360.340.024.340.330]
- Genes, Microbial [G05.360.340.024.340.364]
- Genes, Viral [G05.360.340.024.340.364.875]
- Genes, Immediate-Early [G05.360.340.024.340.364.875.345]
- Genome, Microbial [G05.360.340.358]
- Genes, Microbial [G05.360.340.358.024]
- Genes, Viral [G05.360.340.358.024.875]
- Genes, Immediate-Early [G05.360.340.358.024.875.345]
- Genome, Viral [G05.360.340.358.840]
- Genes, Viral [G05.360.340.358.840.500]
- Genes, Immediate-Early [G05.360.340.358.840.500.345]
Below are MeSH descriptors whose meaning is more specific than "Genes, Immediate-Early".
This graph shows the total number of publications written about "Genes, Immediate-Early" by people in this website by year, and whether "Genes, Immediate-Early" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Genes, Immediate-Early" by people in Profiles.
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E X, Savidis G, Chin CR, Wang S, Lu S, Brass AL, Kowalik TF. A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication. J Virol. 2014 Feb; 88(4):2279-90.
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Dumont JR, Amin E, Poirier GL, Albasser MM, Aggleton JP. Anterior thalamic nuclei lesions in rats disrupt markers of neural plasticity in distal limbic brain regions. Neuroscience. 2012 Nov 08; 224:81-101.
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Kaleem A, Hoessli DC, Ahmad I, Walker-Nasir E, Nasim A, Shakoori AR. Immediate-early gene regulation by interplay between different post-translational modifications on human histone H3. J Cell Biochem. 2008 Feb 15; 103(3):835-51.
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Poirier GL, Amin E, Aggleton JP. Qualitatively different hippocampal subfield engagement emerges with mastery of a spatial memory task by rats. J Neurosci. 2008 Jan 30; 28(5):1034-45.
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Fry CJ, Shogren-Knaak MA, Peterson CL. Histone H3 amino-terminal tail phosphorylation and acetylation: synergistic or independent transcriptional regulatory marks? Cold Spring Harb Symp Quant Biol. 2004; 69:219-26.
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Maier B, Medrano S, Sleight SB, Visconti PE, Scrable H. Developmental association of the synaptic activity-regulated protein arc with the mouse acrosomal organelle and the sperm tail. Biol Reprod. 2003 Jan; 68(1):67-76.
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Spektor BS, Miller DW, Hollingsworth ZR, Kaneko YA, Solano SM, Johnson JM, Penney JB, Young AB, Luthi-Carter R. Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease. Brain Res Mol Brain Res. 2002 Jun 15; 102(1-2):118-28.
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Shih HH, Xiu M, Berasi SP, Sampson EM, Leiter A, Paulson KE, Yee AS. HMG box transcriptional repressor HBP1 maintains a proliferation barrier in differentiated liver tissue. Mol Cell Biol. 2001 Sep; 21(17):5723-32.
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Boulware SL, Bronstein JC, Nordby EC, Weber PC. Identification and characterization of a benzothiophene inhibitor of herpes simplex virus type 1 replication which acts at the immediate early stage of infection. Antiviral Res. 2001 Aug; 51(2):111-25.
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Kohjimoto Y, Honeyman TW, Jonassen J, Gravel K, Kennington L, Scheid CR. Phospholipase A2 mediates immediate early genes in cultured renal epithelial cells: possible role of lysophospholipid. Kidney Int. 2000 Aug; 58(2):638-46.