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Ana Rita Batista PhD

TitleInstructor
InstitutionUMass Chan Medical School
DepartmentNeurology
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentNeurology

    InstitutionT.H. Chan School of Medicine
    DepartmentNeuroNexus Institute


    Collapse Biography 
    Collapse education and training
    University of Porto, Porto, , PortugalMSCBiochemistry
    University of Porto, Porto, , PortugalPHDBiomedical Sciences

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Torres NL, Batista AR, Sousa J, Folia V, Baltos D, Mesquita A, Silva S. Adults With Dyslexia Use Internalised Beat Cues Less Than?Controls When Estimating Interval Length. Dyslexia. 2025 Feb; 31(1):e70001. PMID: 39956969.
      Citations:    
    2. Roy AJ, Leipprandt JR, Patterson JR, Stoll AC, Kemp CJ, Oula ZD, Mola T, Batista AR, Sortwell CE, Sena-Esteves M, Neubig RR. AAV9-Mediated Intrastriatal Delivery of GNAO1 Reduces Hyperlocomotion in Gnao1 Heterozygous R209H Mutant Mice. J Pharmacol Exp Ther. 2024 Jul 18; 390(2):250-259. PMID: 38866563.
      Citations:    
    3. Owusu-Yaw BS, Zhang Y, Garrett L, Yao A, Shing K, Batista AR, Sena-Esteves M, Upadhyay J, Kegel-Gleason K, Todd N. Focused Ultrasound-Mediated Disruption of the Blood-Brain Barrier for AAV9 Delivery in a Mouse Model of Huntington's Disease. Pharmaceutics. 2024 May 24; 16(6). PMID: 38931834.
      Citations:    
    4. Lek A, Wong B, Keeler A, Blackwood M, Ma K, Huang S, Sylvia K, Batista AR, Artinian R, Kokoski D, Parajuli S, Putra J, Carreon CK, Lidov H, Woodman K, Pajusalu S, Spinazzola JM, Gallagher T, LaRovere J, Balderson D, Black L, Sutton K, Horgan R, Lek M, Flotte T. Death after High-Dose rAAV9 Gene Therapy in a Patient with Duchenne's Muscular Dystrophy. N Engl J Med. 2023 09 28; 389(13):1203-1210. PMID: 37754285.
      Citations: 13     Fields:    Translation:Humans
    5. Gross AL, Gray-Edwards HL, Bebout CN, Ta NL, Nielsen K, Brunson BL, Lopez Mercado KR, Osterhoudt DE, Batista AR, Maitland S, Seyfried TN, Sena-Esteves M, Martin DR. Intravenous delivery of adeno-associated viral gene therapy in feline GM1 gangliosidosis. Brain. 2022 04 18; 145(2):655-669. PMID: 34410345.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    6. Flotte TR, Cataltepe O, Puri A, Batista AR, Moser R, McKenna-Yasek D, Douthwright C, Gernoux G, Blackwood M, Mueller C, Tai PWL, Jiang X, Bateman S, Spanakis SG, Parzych J, Keeler AM, Abayazeed A, Rohatgi S, Gibson L, Finberg R, Barton BA, Vardar Z, Shazeeb MS, Gounis M, Tifft CJ, Eichler FS, Brown RH, Martin DR, Gray-Edwards HL, Sena-Esteves M. AAV gene therapy for Tay-Sachs disease. Nat Med. 2022 02; 28(2):251-259. PMID: 35145305.
      Citations: 28     Fields:    Translation:HumansCells
    7. Batista AR. Gene Therapy for Huntington's Disease: The Future Is in Gene Editing. Hum Gene Ther. 2022 Jan; 33(1-2):12-13. PMID: 35049370.
      Citations: 1     Fields:    Translation:Humans
    8. Taghian T, Batista AR, Kamper S, Caldwell M, Lilley L, Li H, Rodriguez P, Mesa K, Zheng S, King RM, Gounis MJ, Todeasa S, Maguire A, Martin DR, Sena-Esteves M, Meade TJ, Gray-Edwards HL. Real-time MR tracking of AAV gene therapy with ?gal-responsive MR probe in a murine model of GM1-gangliosidosis. Mol Ther Methods Clin Dev. 2021 Dec 10; 23:128-134. PMID: 34703836.
      Citations:    
    9. Batista AR, Flotte TR. In?vivo gene editing works in humans: Results of a phase 1 clinical trial for TTR amyloidosis. Mol Ther. 2021 09 01; 29(9):2633-2634. PMID: 34433081.
      Citations: 1     Fields:    Translation:Humans
    10. Lahey HG, Webber CJ, Golebiowski D, Izzo CM, Horn E, Taghian T, Rodriguez P, Batista AR, Ellis LE, Hwang M, Martin DR, Gray-Edwards H, Sena-Esteves M. Pronounced Therapeutic Benefit of a Single Bidirectional AAV Vector Administered Systemically in Sandhoff Mice. Mol Ther. 2020 10 07; 28(10):2150-2160. PMID: 32592687.
      Citations: 12     Fields:    Translation:AnimalsCells
    11. Gray-Edwards HL, Maguire AS, Salibi N, Ellis LE, Voss TL, Diffie EB, Koehler J, Randle AN, Taylor AR, Brunson BL, Denney TS, Beyers RJ, Gentry AS, Gross AL, Batista AR, Sena-Esteves M, Martin DR. 7T MRI Predicts Amelioration of Neurodegeneration in the Brain after AAV Gene Therapy. Mol Ther Methods Clin Dev. 2020 Jun 12; 17:258-270. PMID: 31970203.
      Citations:    
    12. Batista AR, King OD, Reardon CP, Davis C, Philip V, Gray-Edwards H, Aronin N, Lutz C, Landers J, Sena-Esteves M. Ly6a Differential Expression in Blood-Brain Barrier Is Responsible for Strain Specific Central Nervous System Transduction Profile of AAV-PHP.B. Hum Gene Ther. 2020 01; 31(1-2):90-102. PMID: 31696742.
      Citations: 39     Fields:    Translation:AnimalsCells
    13. Taghian T, Marosfoi MG, Puri AS, Cataltepe OI, King RM, Diffie EB, Maguire AS, Martin DR, Fernau D, Batista AR, Kuchel T, Christou C, Perumal R, Chandra S, Gamlin PD, Bertrand SG, Flotte TR, McKenna-Yasek D, Tai PWL, Aronin N, Gounis MJ, Sena-Esteves M, Gray-Edwards HL. A Safe and Reliable Technique for CNS Delivery of AAV Vectors in the Cisterna Magna. Mol Ther. 2020 02 05; 28(2):411-421. PMID: 31813800.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    14. Batista AR, Gianni D, Ventosa M, Coelho AV, Almeida MR, Sena-Esteves M, Saraiva MJ. Gene therapy approach to FAP: in vivo influence of T119M in TTR deposition in a transgenic V30M mouse model. Gene Ther. 2014 Dec; 21(12):1041-50. PMID: 25273354.
      Citations:    
    15. Batista AR, Sena-Esteves M, Saraiva MJ. Hepatic production of transthyretin L12P leads to intracellular lysosomal aggregates in a new somatic transgenic mouse model. Biochim Biophys Acta. 2013 Aug; 1832(8):1183-93. PMID: 23579071.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    16. Macedo B, Magalh?es J, Batista AR, Saraiva MJ. Carvedilol treatment reduces transthyretin deposition in a familial amyloidotic polyneuropathy mouse model. Pharmacol Res. 2010 Dec; 62(6):514-22. PMID: 20692343.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    17. Macedo B, Batista AR, Ferreira N, Almeida MR, Saraiva MJ. Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy. Biochim Biophys Acta. 2008 Sep; 1782(9):517-22. PMID: 18572024.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    18. Macedo B, Batista AR, do Amaral JB, Saraiva MJ. Biomarkers in the assessment of therapies for familial amyloidotic polyneuropathy. Mol Med. 2007 Nov-Dec; 13(11-12):584-91. PMID: 17932549.
      Citations: 11     Fields:    Translation:Animals
    19. Teixeira L, Botelho AS, Batista AR, Meireles CS, Ribeiro A, Domingues HS, Correia Da Costa JM, Castro AG, Faustino AM, Vilanova M. Analysis of the immune response to Neospora caninum in a model of intragastric infection in mice. Parasite Immunol. 2007 Jan; 29(1):23-36. PMID: 17187652.
      Citations:    
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