"Ataxin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.
| Descriptor ID |
D000067698
|
| MeSH Number(s) |
D12.776.157.725.452.125 D12.776.631.069.750 D12.776.660.075.750 D12.776.664.962.452.125
|
| Concept/Terms |
Ataxin-2- Ataxin-2
- Ataxin 2
- Ataxin-2 Protein
- Ataxin 2 Protein
- Protein, Ataxin-2
- Spinocerebellar Ataxia Type 2 Protein
- ATXN2 Protein
- Protein, ATXN2
- Atx-2 Protein
- Atx 2 Protein
- Protein, Atx-2
- SCA2 Protein
- Protein, SCA2
|
Below are MeSH descriptors whose meaning is more general than "Ataxin-2".
Below are MeSH descriptors whose meaning is more specific than "Ataxin-2".
This graph shows the total number of publications written about "Ataxin-2" by people in this website by year, and whether "Ataxin-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Ataxin-2" by people in Profiles.
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Chitre M, Emery P. ATXN2 is a target of N-terminal proteolysis. PLoS One. 2023; 18(12):e0296085.
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Glass JD, Dewan R, Ding J, Gibbs JR, Dalgard C, Keagle PJ, Garc?a-Redondo A, Traynor BJ, Chia R, Landers JE. ATXN2 intermediate expansions in amyotrophic lateral sclerosis. Brain. 2022 08 27; 145(8):2671-2676.
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Gnazzo MM, Uhlemann EE, Villarreal AR, Shirayama M, Dominguez EG, Skop AR. The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4. Mol Biol Cell. 2016 10 15; 27(20):3052-3064.
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March ZM, King OD, Shorter J. Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease. Brain Res. 2016 09 15; 1647:9-18.