Synthetic Lethal Mutations
"Synthetic Lethal Mutations" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutations in genes which lead to cell or organism death when occurring in combination with mutations in one or more other genes.
| Descriptor ID |
D000072020
|
| MeSH Number(s) |
G05.365.590.917
|
| Concept/Terms |
Synthetic Lethal Mutations- Synthetic Lethal Mutations
- Synthetic Lethal Mutation
- Lethal Mutation, Synthetic
- Lethal Mutations, Synthetic
- Mutation, Synthetic Lethal
- Mutations, Synthetic Lethal
|
Below are MeSH descriptors whose meaning is more general than "Synthetic Lethal Mutations".
Below are MeSH descriptors whose meaning is more specific than "Synthetic Lethal Mutations".
This graph shows the total number of publications written about "Synthetic Lethal Mutations" by people in this website by year, and whether "Synthetic Lethal Mutations" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synthetic Lethal Mutations" by people in Profiles.
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Zhang Y, Wu MJ, Lu WC, Li YC, Chang CJ, Yang JY. Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer. Cell Metab. 2024 01 02; 36(1):193-208.e8.
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Ohkuni K, Suva E, Au WC, Walker RL, Levy-Myers R, Meltzer PS, Baker RE, Basrai MA. Deposition of Centromeric Histone H3 Variant CENP-A/Cse4 into Chromatin Is Facilitated by Its C-Terminal Sumoylation. Genetics. 2020 04; 214(4):839-854.
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Viny AD, Bowman RL, Liu Y, Lavall?e VP, Eisman SE, Xiao W, Durham BH, Navitski A, Park J, Braunstein S, Alija B, Karzai A, Csete IS, Witkin M, Azizi E, Baslan T, Ott CJ, Pe'er D, Dekker J, Koche R, Levine RL. Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation. Cell Stem Cell. 2019 11 07; 25(5):682-696.e8.