"Codon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of three nucleotides in a protein coding sequence that specifies individual amino acids or a termination signal (CODON, TERMINATOR). Most codons are universal, but some organisms do not produce the transfer RNAs (RNA, TRANSFER) complementary to all codons. These codons are referred to as unassigned codons (CODONS, NONSENSE).
| Descriptor ID |
D003062
|
| MeSH Number(s) |
D13.444.735.544.355 G05.360.335.355 G05.360.340.024.340.137.190
|
| Concept/Terms |
Sense Codon- Sense Codon
- Codons, Sense
- Sense Codons
- Codon, Sense
|
Below are MeSH descriptors whose meaning is more general than "Codon".
Below are MeSH descriptors whose meaning is more specific than "Codon".
This graph shows the total number of publications written about "Codon" by people in this website by year, and whether "Codon" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 2 | 3 |
| 2015 | 2 | 1 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 2 | 1 | 3 |
| 2020 | 2 | 1 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
| 2025 | 2 | 1 | 3 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Codon" by people in Profiles.
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Sorokin I, Korostelev AA. A Unified Mechanism of +1 Ribosomal Frameshifting. Cold Spring Harb Perspect Biol. 2026 Aug 25; 18(9).
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Muraski MJ, Guinto FC, Nilsson EM, Dabdoub JB, Robinson SC, Jiang Y, Shen Z, Alexander RW. The bacterial tRNA-modifying enzyme tRNAIle lysidine synthetase is genetically conserved but catalytically variable. J Biol Chem. 2025 10; 301(10):110688.
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Ramirez-Moya J, Antika TR, Liu Q, Xiong X, Ali R, Gutierrez A, Gregory RI. The tRNA Editing Complex ADAT2/3 Promotes Cancer Cell Growth and Codon-biased mRNA Translation. J Mol Biol. 2025 Nov 01; 437(21):169414.
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Ravi S, Sharma T, Yip M, Yang H, Xie J, Gao G, Tai PWL. A deep learning model trained on expressed transcripts across different tissue types reveals cell-type codon-optimization preferences. Nucleic Acids Res. 2025 Mar 20; 53(6).
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Cui J, Sendinc E, Liu Q, Kim S, Fang JY, Gregory RI. m3C32 tRNA modification controls serine codon-biased mRNA translation, cell cycle, and DNA-damage response. Nat Commun. 2024 07 10; 15(1):5775.
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Wu C, Iyer S, Wolfe SA, Jacobson A. Functional restoration of mouse Nf1 nonsense alleles in differentiated cultured neurons. J Hum Genet. 2022 Nov; 67(11):661-668.
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Orellana EA, Siegal E, Gregory RI. tRNA dysregulation and disease. Nat Rev Genet. 2022 11; 23(11):651-664.
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Martin DP, Weaver S, Tegally H, San JE, Shank SD, Wilkinson E, Lucaci AG, Giandhari J, Naidoo S, Pillay Y, Singh L, Lessells RJ, Gupta RK, Wertheim JO, Nekturenko A, Murrell B, Harkins GW, Lemey P, MacLean OA, Robertson DL, de Oliveira T, Kosakovsky Pond SL. The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages. Cell. 2021 09 30; 184(20):5189-5200.e7.
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Shu H, Donnard E, Liu B, Jung S, Wang R, Richter JD. FMRP links optimal codons to mRNA stability in neurons. Proc Natl Acad Sci U S A. 2020 12 01; 117(48):30400-30411.
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Liu Q, Shvarts T, Sliz P, Gregory RI. RiboToolkit: an integrated platform for analysis and annotation of ribosome profiling data to decode mRNA translation at codon resolution. Nucleic Acids Res. 2020 07 02; 48(W1):W218-W229.