DNA End-Joining Repair

"DNA End-Joining Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The repair of DOUBLE-STRAND DNA BREAKS by rejoining the broken ends of DNA to each other directly.

Descriptor ID	D059766
MeSH Number(s)	G02.111.222.200 G05.219.200
Concept/Terms	DNA End-Joining Repair DNA End-Joining Repair DNA End Joining Repair End-Joining Repair, DNA Repair, DNA End-Joining End-Joining DNA Repair DNA Repair, End-Joining End Joining DNA Repair Repair, End-Joining DNA Microhomology-Mediated End Joining Repair Microhomology-Mediated End Joining Repair Microhomology Mediated End Joining Repair MMEJ DNA Repair DNA Repair, MMEJ Repair, MMEJ DNA Non-Homologous DNA End-Joining Non-Homologous DNA End-Joining DNA End-Joining, Non-Homologous End-Joining, Non-Homologous DNA Non Homologous DNA End Joining Nonhomologous DNA End-Joining DNA End-Joining, Nonhomologous Nonhomologous DNA End Joining NHEJ DNA Repair DNA Repair, NHEJ Repair, NHEJ DNA

Below are MeSH descriptors whose meaning is more general than "DNA End-Joining Repair".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
DNA Repair [G02.111.222]
DNA End-Joining Repair [G02.111.222.200]
Genetic Phenomena [G05]
DNA Repair [G05.219]
DNA End-Joining Repair [G05.219.200]

Below are MeSH descriptors whose meaning is related to "DNA End-Joining Repair".

Below are MeSH descriptors whose meaning is more specific than "DNA End-Joining Repair".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA End-Joining Repair" by people in this website by year, and whether "DNA End-Joining Repair" was a major or minor topic of these publications.

Bar chart showing 14 publications over 10 distinct years, with a maximum of 3 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2012	0	1	1
2013	2	1	3
2014	0	1	1
2015	0	2	2
2017	0	1	1
2018	0	1	1
2019	2	0	2
2021	0	1	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "DNA End-Joining Repair" by people in Profiles.

Min J, Zhao J, Zagelbaum J, Lee J, Takahashi S, Cummings P, Schooley A, Dekker J, Gottesman ME, Rabadan R, Gautier J. Mechanisms of insertions at a DNA double-strand break. Mol Cell. 2023 07 20; 83(14):2434-2448.e7.

View in: PubMed
Zagelbaum J, Schooley A, Zhao J, Schrank BR, Callen E, Zha S, Gottesman ME, Nussenzweig A, Rabadan R, Dekker J, Gautier J. Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nat Struct Mol Biol. 2023 01; 30(1):99-106.

View in: PubMed
Banerjee R, Liu M, Bellile E, Schmitd LB, Goto M, Hutchinson MND, Singh P, Zhang S, Damodaran DPV, Nyati MK, Spector ME, Ward B, Wolf G, Casper K, Mierzwa M, D'Silva NJ. Phosphorylation of TRIP13 at Y56 induces radiation resistance but sensitizes head and neck cancer to cetuximab. Mol Ther. 2022 01 05; 30(1):468-484.

View in: PubMed
Black SJ, Ozdemir AY, Kashkina E, Kent T, Rusanov T, Ristic D, Shin Y, Suma A, Hoang T, Chandramouly G, Siddique LA, Borisonnik N, Sullivan-Reed K, Mallon JS, Skorski T, Carnevale V, Murakami KS, Wyman C, Pomerantz RT. Molecular basis of microhomology-mediated end-joining by purified full-length Pol?. Nat Commun. 2019 09 27; 10(1):4423.

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Iyer S, Suresh S, Guo D, Daman K, Chen JCJ, Liu P, Zieger M, Luk K, Roscoe BP, Mueller C, King OD, Emerson CP, Wolfe SA. Precise therapeutic gene correction by a simple nuclease-induced double-stranded break. Nature. 2019 04; 568(7753):561-565.

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Yoon Y, Wang D, Tai PWL, Riley J, Gao G, Rivera-P?rez JA. Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses. Nat Commun. 2018 01 29; 9(1):412.

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Carmona LM, Schatz DG. New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination. FEBS J. 2017 06; 284(11):1590-1605.

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Zhuang J, Weng Z. Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes. Nucleic Acids Res. 2015 Sep 30; 43(17):8146-56.

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Kadungure T, Ucher AJ, Linehan EK, Schrader CE, Stavnezer J. Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination. PLoS One. 2015; 10(8):e0134397.

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Wang D, Gao G. State-of-the-art human gene therapy: part II. Gene therapy strategies and clinical applications. Discov Med. 2014 Sep; 18(98):151-61.

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