"Securin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Securin is involved in the control of the metaphase-anaphase transition during MITOSIS. It promotes the onset of anaphase by blocking SEPARASE function and preventing proteolysis of cohesin and separation of sister CHROMATIDS. Overexpression of securin is associated with NEOPLASTIC CELL TRANSFORMATION and tumor formation.
- Pituitary Tumor-Transforming Proteins
- Pituitary Tumor Transforming Proteins
- PTTG Protein
- Pituitary Tumor-Transforming Gene Protein
Below are MeSH descriptors whose meaning is more general than "Securin".
Below are MeSH descriptors whose meaning is more specific than "Securin".
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