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Chloroquine interferes with lipopolysaccharide-induced TNF-alpha gene expression by a nonlysosomotropic mechanism.
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Chloroquine interferes with lipopolysaccharide-induced TNF-alpha gene expression by a nonlysosomotropic mechanism.
Weber SM, Levitz SM. Chloroquine interferes with lipopolysaccharide-induced TNF-alpha gene expression by a nonlysosomotropic mechanism. J Immunol. 2000 Aug 01; 165(3):1534-40.
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PubMed
subject areas
Anti-Bacterial Agents
Biological Transport
Cell Nucleus
Chemokine CCL5
Chloroquine
DNA-Binding Proteins
Dose-Response Relationship, Drug
Dose-Response Relationship, Immunologic
Gene Expression Regulation
Humans
Hydrogen-Ion Concentration
Immunosuppressive Agents
Interleukin-1
Interleukin-6
Leukocytes, Mononuclear
Lipopolysaccharides
Lysosomes
Macrolides
NF-kappa B
NF-kappa B p50 Subunit
Protein Biosynthesis
Protein Processing, Post-Translational
RNA, Messenger
Transcription Factor RelA
Transcription, Genetic
Tumor Necrosis Factor-alpha
authors with profiles
Stuart M Levitz MD