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During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities.
Enhanced responsiveness to T-cell help causes loss of B-lymphocyte tolerance to a ?-cell neo-self-antigen in type 1 diabetes prone NOD mice.
Innate immune recognition of lipopolysaccharide by endothelial cells.
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Innate immune recognition of lipopolysaccharide by endothelial cells.
Henneke P, Golenbock DT. Innate immune recognition of lipopolysaccharide by endothelial cells. Crit Care Med. 2002 May; 30(5 Suppl):S207-13.
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PubMed
subject areas
Antigens, Surface
DNA, Bacterial
Drosophila Proteins
Endothelium, Vascular
Gram-Negative Bacteria
Humans
Lipopolysaccharides
Lymphocyte Antigen 96
Membrane Glycoproteins
Receptors, Cell Surface
Sepsis
Signal Transduction
Toll-Like Receptor 4
Toll-Like Receptors
authors with profiles
Douglas T Golenbock MD