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Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation.
Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors.
Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.
An endocytic pathway as a target of tubby for regulation of fat storage.
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
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HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.
Yu M, Wang H, Ding A, Golenbock DT, Latz E, Czura CJ, Fenton MJ, Tracey KJ, Yang H. HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock. 2006 Aug; 26(2):174-9.
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PubMed
subject areas
Animals
Antibodies, Monoclonal
Blood Cells
Cell Line
CHO Cells
Cricetinae
Cricetulus
Dose-Response Relationship, Drug
Dose-Response Relationship, Immunologic
Glycation End Products, Advanced
HMGB1 Protein
Humans
Interleukin-8
Mice
Mice, Knockout
Receptor for Advanced Glycation End Products
Receptors, Immunologic
Signal Transduction
Toll-Like Receptor 2
Toll-Like Receptor 4
Tumor Necrosis Factor-alpha
authors with profiles
Eicke Latz MD
Douglas T Golenbock MD