Interleukin-8

"Interleukin-8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.

Descriptor ID	D016209
MeSH Number(s)	D12.644.276.374.200.120.800 D12.644.276.374.465.312 D12.776.467.374.200.120.800 D12.776.467.374.465.246 D23.125.300.120.800 D23.469.200.120.800 D23.529.374.200.120.800 D23.529.374.465.312
Concept/Terms	Interleukin-8 Interleukin-8 Interleukin 8 IL8 Monocyte-Derived Neutrophil Chemotactic Factor Neutrophil Activation Factor Neutrophil-Activating Peptide, Lymphocyte-Derived Lymphocyte-Derived Neutrophil-Activating Peptide Neutrophil Activating Peptide, Lymphocyte Derived Neutrophil-Activating Peptide, Monocyte-Derived Monocyte-Derived Neutrophil-Activating Peptide Neutrophil Activating Peptide, Monocyte Derived Alveolar Macrophage Chemotactic Factor-I Alveolar Macrophage Chemotactic Factor I AMCF-I Anionic Neutrophil-Activating Peptide Anionic Neutrophil Activating Peptide Neutrophil-Activating Peptide, Anionic Peptide, Anionic Neutrophil-Activating Chemokine CXCL8 CXCL8, Chemokine Chemokines, CXCL8 CXCL8 Chemokines Chemotactic Factor, Macrophage-Derived Chemotactic Factor, Macrophage Derived Macrophage-Derived Chemotactic Factor Chemotactic Factor, Neutrophil Neutrophil Chemotactic Factor Chemotactic Factor, Neutrophil, Monocyte-Derived CXCL8 Chemokine Chemokine, CXCL8 Granulocyte Chemotactic Peptide-Interleukin-8 Chemotactic Peptide-Interleukin-8, Granulocyte Granulocyte Chemotactic Peptide Interleukin 8 IL-8

Below are MeSH descriptors whose meaning is more general than "Interleukin-8".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Chemokines [D12.644.276.374.200]
Chemokines, CXC [D12.644.276.374.200.120]
Interleukin-8 [D12.644.276.374.200.120.800]
Interleukins [D12.644.276.374.465]
Interleukin-8 [D12.644.276.374.465.312]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Chemokines [D12.776.467.374.200]
Chemokines, CXC [D12.776.467.374.200.120]
Interleukin-8 [D12.776.467.374.200.120.800]
Interleukins [D12.776.467.374.465]
Interleukin-8 [D12.776.467.374.465.246]
Biological Factors [D23]
Chemotactic Factors [D23.125]
Chemokines [D23.125.300]
Chemokines, CXC [D23.125.300.120]
Interleukin-8 [D23.125.300.120.800]
Inflammation Mediators [D23.469]
Chemokines [D23.469.200]
Chemokines, CXC [D23.469.200.120]
Interleukin-8 [D23.469.200.120.800]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Chemokines [D23.529.374.200]
Chemokines, CXC [D23.529.374.200.120]
Interleukin-8 [D23.529.374.200.120.800]
Interleukins [D23.529.374.465]
Interleukin-8 [D23.529.374.465.312]

Below are MeSH descriptors whose meaning is more specific than "Interleukin-8".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-8" by people in this website by year, and whether "Interleukin-8" was a major or minor topic of these publications.

Bar chart showing 71 publications over 27 distinct years, with a maximum of 6 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	3	3
1996	2	0	2
1998	1	2	3
1999	1	2	3
2000	0	1	1
2001	0	1	1
2002	2	1	3
2003	0	3	3
2004	1	3	4
2005	2	2	4
2006	0	3	3
2007	0	6	6
2008	1	4	5
2009	0	3	3
2010	1	2	3
2011	0	2	2
2012	1	2	3
2013	0	1	1
2014	1	1	2
2015	1	2	3
2016	2	1	3
2017	0	3	3
2018	0	1	1
2019	0	2	2
2020	1	0	1
2023	0	1	1
2024	2	0	2

Below are the most recent publications written about "Interleukin-8" by people in Profiles.

Reedy JL, Jensen KN, Crossen AJ, Basham KJ, Ward RA, Reardon CM, Brown Harding H, Hepworth OW, Simaku P, Kwaku GN, Tone K, Willment JA, Reid DM, Stappers MHT, Brown GD, Rajagopal J, Vyas JM. Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing. Nat Commun. 2024 Jul 10; 15(1):5817.

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O'Reilly ME, Ho S, Coronel J, Zhu L, Liu W, Xue C, Kim E, Cynn E, Matias CV, Soni RK, Wang C, Ionita-Laza I, Bauer RC, Ross L, Zhang Y, Corvera S, Fried SK, Reilly MP. linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability. Cell Rep. 2024 05 28; 43(5):114240.

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Zhu X, Gebo KA, Abraham AG, Habtehyimer F, Patel EU, Laeyendecker O, Gniadek TJ, Fernandez RE, Baker OR, Ram M, Cachay ER, Currier JS, Fukuta Y, Gerber JM, Heath SL, Meisenberg B, Huaman MA, Levine AC, Shenoy A, Anjan S, Blair JE, Cruser D, Forthal DN, Hammitt LL, Kassaye S, Mosnaim GS, Patel B, Paxton JH, Raval JS, Sutcliffe CG, Abinante M, Broderick P, Cluzet V, Cordisco ME, Greenblatt B, Petrini J, Rausch W, Shade D, Lane K, Gawad AL, Klein SL, Pekosz A, Shoham S, Casadevall A, Bloch EM, Hanley D, Sullivan DJ, Tobian AAR. Dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA: a prospective cohort study. Lancet Microbe. 2023 09; 4(9):e692-e703.

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Sharma A, Raman V, Lee J, Forbes NS. Mucus blocks probiotics but increases penetration of motile pathogens and induces TNF-a and IL-8 secretion. Biotechnol Bioeng. 2020 08; 117(8):2540-2555.

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Zhang Z, Xiao H, Zhou P. Allergenicity suppression of tropomyosin from Exopalaemon modestus by glycation with saccharides of different molecular sizes. Food Chem. 2019 Aug 01; 288:268-275.

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Alvarez-Silva C, Schierwagen R, Pohlmann A, Magdaleno F, Uschner FE, Ryan P, Vehreschild MJGT, Claria J, Latz E, Lelouvier B, Arumugam M, Trebicka J. Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis. Front Immunol. 2019; 10:69.

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Zhang Z, Xiao H, Zhang X, Zhou P. Conformation, allergenicity and human cell allergy sensitization of tropomyosin from Exopalaemon modestus: Effects of deglycosylation and Maillard reaction. Food Chem. 2019 Mar 15; 276:520-527.

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Han MK, Quibrera PM, Carretta EE, Barr RG, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL, Criner G, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Krishnan JA, Martinez CH, Pirozzi CB, O'Neal WK, Rennard S, Tashkin DP, Wedzicha JA, Woodruff P, Paine R, Martinez FJ. Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017 08; 5(8):619-626.

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Korkmaz FT, Kerr DE. Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS. BMC Genomics. 2017 05 25; 18(1):405.

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Wang K, Liu X, Xiao H, Wang H, Zhang Y. The correlation between inflammatory injury induced by LPS and RAS in EpH4-Ev cells. Int Immunopharmacol. 2017 May; 46:23-30.

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