DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis.

Shell SS, Prestwich EG, Baek SH, Shah RR, Sassetti CM, Dedon PC, Fortune SM. DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis. PLoS Pathog. 2013; 9(7):e1003419.

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subject areas

Animals
Bacterial Load
Bacterial Proteins
Codon, Initiator
DNA Methylation
DNA, Bacterial
Female
Gene Deletion
Gene Expression Profiling
Gene Expression Regulation, Bacterial
Humans
Isoenzymes
Lung
Mice
Mice, Inbred C57BL
Microbial Viability
Mycobacterium tuberculosis
Point Mutation
Site-Specific DNA-Methyltransferase (Adenine-Specific)
Stress, Physiological
Substrate Specificity
Tuberculosis

authors with profiles

Christopher M Sassetti PhD