Gene Deletion

"Gene Deletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.

Descriptor ID	D017353
MeSH Number(s)	G05.365.590.762.320 G05.558.800.320
Concept/Terms	Gene Deletion Gene Deletion Deletion, Gene Deletions, Gene Gene Deletions

Below are MeSH descriptors whose meaning is more general than "Gene Deletion".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Variation [G05.365]
Mutation [G05.365.590]
Sequence Deletion [G05.365.590.762]
Gene Deletion [G05.365.590.762.320]
Mutagenesis [G05.558]
Sequence Deletion [G05.558.800]
Gene Deletion [G05.558.800.320]

Below are MeSH descriptors whose meaning is related to "Gene Deletion".

Below are MeSH descriptors whose meaning is more specific than "Gene Deletion".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gene Deletion" by people in this website by year, and whether "Gene Deletion" was a major or minor topic of these publications.

Bar chart showing 251 publications over 29 distinct years, with a maximum of 20 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	2	3
1998	2	1	3
1999	0	2	2
2000	1	6	7
2001	2	8	10
2002	1	5	6
2003	0	14	14
2004	0	12	12
2005	4	13	17
2006	2	7	9
2007	6	14	20
2008	5	8	13
2009	1	8	9
2010	1	9	10
2011	1	4	5
2012	2	10	12
2013	2	10	12
2014	1	11	12
2015	3	8	11
2016	2	14	16
2017	2	5	7
2018	1	5	6
2019	2	10	12
2020	1	5	6
2021	4	6	10
2023	0	1	1
2024	0	3	3
2025	1	0	1
2026	0	2	2

Below are the most recent publications written about "Gene Deletion" by people in Profiles.

McCormick BK, Barbash DA, Clark AG. The Stellate meiotic drive system of Drosophila melanogaster is active in contemporary populations. Genetics. 2026 Aug 05; 233(4).

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Kado T, Bosworth PH, Jordan J, Freundlich JS, Siegrist MS, Morita YS. ag85A loss promotes free mycolate accumulation and sensitizes plasma membrane domain to disruption. J Bacteriol. 2026 Aug 20; 208(8):e0024026.

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Watson OJ, Tran TN, Zupko RJ, Symons T, Thomson R, Visser T, Rumisha S, Dzianach PA, Hathaway N, Kim I, Juliano JJ, Bailey JA, Slater H, Okell L, Gething P, Ghani A, Boni MF, Parr JB, Cunningham J. Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions. Nat Med. 2025 Oct; 31(10):3372-3379.

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Hathaway NJ, Kim IE, WernsmanYoung N, Hui ST, Crudale R, Liang EY, Nixon CP, Giesbrecht D, Juliano JJ, Parr JB, Bailey JA. Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3. Elife. 2024 Oct 07; 13.

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Cirrincione AM, Poos AM, Ziccheddu B, Kaddoura M, B?rtsch MA, Maclachlan K, Chojnacka M, Diamond B, John L, Reichert P, Huhn S, Blaney P, Gagler D, Rippe K, Zhang Y, Dogan A, Lesokhin AM, Davies F, Goldschmidt H, Fenk R, Weisel KC, Mai EK, Korde N, Morgan GJ, Usmani S, Landgren O, Raab MS, Weinhold N, Maura F. The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma. Blood. 2024 08 15; 144(7):771-783.

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Rogier E, Battle N, Bakari C, Seth MD, Nace D, Herman C, Barakoti A, Madebe RA, Mandara CI, Lyimo BM, Giesbrecht DJ, Popkin-Hall ZR, Francis F, Mbwambo D, Garimo I, Aaron S, Lusasi A, Molteni F, Njau R, Cunningham JA, Lazaro S, Mohamed A, Juliano JJ, Bailey JA, Udhayakumar V, Ishengoma DS. Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients enrolled at 100 health facilities throughout Tanzania: February to July 2021. Sci Rep. 2024 04 08; 14(1):8158.

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Fran?ois R, Kashamuka MM, Banek K, Bala JA, Nkalani M, Kihuma G, Atibu J, Mahilu GE, Thwai KL, Assefa A, Bailey JA, Dinglasan RR, Juliano JJ, Tshefu AK, Parr JB. Plasmodium falciparum with pfhrp2/3 Deletion Not Detected in a 2018-2021 Malaria Longitudinal Cohort Study in Kinshasa Province, Democratic Republic of the Congo. Am J Trop Med Hyg. 2023 08 02; 109(2):273-276.

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Gardner HL, Fenger JM, Roberts RD, London CA. Characterizing the metabolic role of STAT3 in canine osteosarcoma. Vet Comp Oncol. 2022 Dec; 20(4):817-824.

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Kummer MP, Ising C, Kummer C, Sarlus H, Griep A, Vieira-Saecker A, Schwartz S, Halle A, Br?ckner M, H?ndler K, Schultze JL, Beyer M, Latz E, Heneka MT. Microglial PD-1 stimulation by astrocytic PD-L1 suppresses neuroinflammation and Alzheimer's disease pathology. EMBO J. 2021 12 15; 40(24):e108662.

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Feleke SM, Reichert EN, Mohammed H, Brhane BG, Mekete K, Mamo H, Petros B, Solomon H, Abate E, Hennelly C, Denton M, Keeler C, Hathaway NJ, Juliano JJ, Bailey JA, Rogier E, Cunningham J, Aydemir O, Parr JB. Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia. Nat Microbiol. 2021 10; 6(10):1289-1299.

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