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The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral production.
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A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication.
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A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication.
E X, Savidis G, Chin CR, Wang S, Lu S, Brass AL, Kowalik TF. A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication. J Virol. 2014 Feb; 88(4):2279-90.
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PubMed
subject areas
Ataxia Telangiectasia Mutated Proteins
Cytomegalovirus
DNA-Binding Proteins
Feedback, Physiological
Fluorescent Antibody Technique
Gene Expression Regulation, Viral
Genes, Immediate-Early
Humans
Immunoblotting
Mutation
Real-Time Polymerase Chain Reaction
RNA Interference
RNA, Small Interfering
Transduction, Genetic
Transfection
Virus Replication
authors with profiles
Timothy F Kowalik PhD
Shan Lu MD, PhD