Dextran Sulfate

"Dextran Sulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.

Descriptor ID	D016264
MeSH Number(s)	D09.698.365.272.300
Concept/Terms	Dextran Sulfate Dextran Sulfate Sulfate, Dextran Dextran Sulfate Sodium Dextran Sulfate Sodium Sulfate Sodium, Dextran Sodium Dextran Sulfate Dextran Sulfate, Sodium Sulfate, Sodium Dextran

Below are MeSH descriptors whose meaning is more general than "Dextran Sulfate".

Chemicals and Drugs [D]
Carbohydrates [D09]
Polysaccharides [D09.698]
Glucans [D09.698.365]
Dextrans [D09.698.365.272]
Dextran Sulfate [D09.698.365.272.300]

Below are MeSH descriptors whose meaning is related to "Dextran Sulfate".

Below are MeSH descriptors whose meaning is more specific than "Dextran Sulfate".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dextran Sulfate" by people in this website by year, and whether "Dextran Sulfate" was a major or minor topic of these publications.

Bar chart showing 29 publications over 15 distinct years, with a maximum of 6 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2002	1	0	1
2009	1	1	2
2010	0	1	1
2011	0	1	1
2013	0	1	1
2015	0	1	1
2016	0	1	1
2018	0	3	3
2019	0	5	5
2020	0	1	1
2021	0	3	3
2023	0	1	1
2024	5	1	6
2025	1	0	1

Below are the most recent publications written about "Dextran Sulfate" by people in Profiles.

Wang W, Wang Y, Sanidad KZ, Wang Y, Zhang J, Yang W, Sun Q, Bayram I, Song R, Yang H, Johnson D, Sherman HL, Kim D, Minter LM, Wong JJ, Zeng MY, Decker EA, Zhang G. Oxidized Polyunsaturated Fatty Acid Promotes Colitis and Colitis-Associated Tumorigenesis in Mice. J Crohns Colitis. 2025 Mar 05; 19(3).

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Li X, Duan W, Zhu Y, Ji R, Feng K, Kathuria Y, Xiao H, Yu Y, Cao Y. Transcriptomics and metabolomics reveal the alleviation effect of pectic polysaccharide on dextran sodium sulfate-induced colitis mice. Int J Biol Macromol. 2025 Feb; 288:138755.

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Yi L, Han Y, Shen P, Du H, Guo X, Zhou Z, Xiao H. Dietary Porphyra tenera ameliorated dextran sodium sulfate-induced colitis in mice via modulating gut microbiota dysbiosis. Food Chem. 2024 Dec 15; 461:140832.

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Qiu Z, Xiang L, Han Y, Zhang B, Qiao X, Zheng Z, Xiao H. Structure-anti-inflammatory activity relationship of garlic fructans in mice with dextran sulfate sodium-induced colitis: Impact of chain length. Carbohydr Polym. 2024 Dec 15; 346:122582.

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Li X, Chen Y, Peng X, Zhu Y, Duan W, Ji R, Xiao H, Li X, Liu G, Yu Y, Cao Y. Anti-inflammation mechanisms of a homogeneous polysaccharide from Phyllanthus emblica L. on DSS induced colitis mice via the gut microbiota and metabolites alteration. Food Chem. 2024 Nov 30; 459:140346.

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Ma G, Tao Q, Li X, Han Y, Du H, Hu Q, Xiao H. Metabolomics study of dietary Pleurotus eryngii ?-type glycosidic polysaccharide on colitis induced by dextran sodium sulfate in mice - Exploration for the potential metabolic indicators in urine and serum. Food Chem. 2024 Nov 15; 458:140195.

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Gu Q, Jiang Z, Li K, Li Y, Yan X, McClements DJ, Ma C, Liu F. Effectiveness of probiotic- and fish oil-loaded water-in-oil-in-water (W1/O/W2) emulsions at alleviating ulcerative colitis. Food Funct. 2024 Jun 04; 15(11):5797-5812.

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Xie P, Chen B, Ran J, Zhan M, Du H, Hong F, Lu M, Cao Y, Xiao H, Song M. Dietary 5-demethylnobiletin attenuated dextran sulfate sodium-induced colitis in mice by inhibiting immune response and regulating gut microbiota. Food Funct. 2023 Jul 03; 14(13):6248-6261.

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Chen B, Luo J, Han Y, Du H, Liu J, He W, Zhu J, Xiao J, Wang J, Cao Y, Xiao H, Song M. Dietary Tangeretin Alleviated Dextran Sulfate Sodium-Induced Colitis in Mice via Inhibiting Inflammatory Response, Restoring Intestinal Barrier Function, and Modulating Gut Microbiota. J Agric Food Chem. 2021 Jul 14; 69(27):7663-7674.

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Banskota S, Wang H, Kwon YH, Gautam J, Gurung P, Haq S, Hassan FMN, Bowdish DM, Kim JA, Carling D, Fullerton MD, Steinberg GR, Khan WI. Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK. Inflamm Bowel Dis. 2021 05 17; 27(6):914-926.

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