"Oligonucleotide Probes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
| Descriptor ID |
D015345
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| MeSH Number(s) |
D13.444.600.601 D27.505.259.750.600.650 D27.720.470.530.600.650
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oligonucleotide Probes".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotide Probes".
This graph shows the total number of publications written about "Oligonucleotide Probes" by people in this website by year, and whether "Oligonucleotide Probes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 3 | 4 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Oligonucleotide Probes" by people in Profiles.
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Kordon MM, Zarebski M, Solarczyk K, Ma H, Pederson T, Dobrucki JW. STRIDE-a fluorescence method for direct, specific in situ detection of individual single- or double-strand DNA breaks in fixed cells. Nucleic Acids Res. 2020 02 20; 48(3):e14.
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Li C, Zamore PD. Analysis of Small RNAs by Northern Hybridization. Cold Spring Harb Protoc. 2018 08 01; 2018(8).
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Wang J, Tai W, Angione SL, John AR, Opal SM, Artenstein AW, Tripathi A. Subtyping clinical specimens of influenza A virus by use of a simple method to amplify RNA targets. J Clin Microbiol. 2013 Oct; 51(10):3324-30.
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Byron M, Hall LL, Lawrence JB. A multifaceted FISH approach to study endogenous RNAs and DNAs in native nuclear and cell structures. Curr Protoc Hum Genet. 2013 Jan; Chapter 4:Unit 4.15.
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Wang Y, Chen L, Liu X, Cheng D, Liu G, Liu Y, Dou S, Hnatowich DJ, Rusckowski M. Detection of Aspergillus fumigatus pulmonary fungal infections in mice with (99m)Tc-labeled MORF oligomers targeting ribosomal RNA. Nucl Med Biol. 2013 Jan; 40(1):89-96.
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Bogdanov AA, Metelev V, Zhang S, Kumar AT. Sensing of transcription factor binding via cyanine dye pair fluorescence lifetime changes. Mol Biosyst. 2012 Aug; 8(8):2166-73.
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Pagano JM, Clingman CC, Ryder SP. Quantitative approaches to monitor protein-nucleic acid interactions using fluorescent probes. RNA. 2011 Jan; 17(1):14-20.
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Nugen SR, Leonard B, Baeumner AJ. Application of a unique server-based oligonucleotide probe selection tool toward a novel biosensor for the detection of Streptococcus pyogenes. Biosens Bioelectron. 2007 May 15; 22(11):2442-8.
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Lee RC, Hammell CM, Ambros V. Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans. RNA. 2006 Apr; 12(4):589-97.
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Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ. The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14114-9.