A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions.
Xue W, Kitzing T, Roessler S, Zuber J, Krasnitz A, Schultz N, Revill K, Weissmueller S, Rappaport AR, Simon J, Zhang J, Luo W, Hicks J, Zender L, Wang XW, Powers S, Wigler M, Lowe SW. A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):8212-7.
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Animals
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Carcinoma, Hepatocellular
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Cell Line, Transformed
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Cell Line, Tumor
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Chromosomes, Human, Pair 8
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Female
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Gene Deletion
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Gene Expression Regulation, Neoplastic
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Genes, Tumor Suppressor
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Genomics
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Haploinsufficiency
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Humans
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Liver
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Liver Neoplasms, Experimental
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Mice
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Mice, Inbred C57BL
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Mice, Nude
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Monosomy
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RNA Interference
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Stem Cells