rab3A GTP-Binding Protein
"rab3A GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The most abundant member of the RAB3 GTP-BINDING PROTEINS. It is involved in calcium-dependent EXOCYTOSIS and is localized to neurons and neuroendocrine cells. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020826
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| MeSH Number(s) |
D08.811.277.040.330.300.400.400.100.500 D12.644.360.525.400.100.100 D12.776.157.325.515.400.100.100 D12.776.476.525.400.100.100
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| Concept/Terms |
rab3A GTP-Binding Protein- rab3A GTP-Binding Protein
- GTP-Binding Protein, rab3A
- rab3A GTP Binding Protein
- smg p25A Protein
- p25A Protein, smg
- smg25a GTP Binding Protein
- rab3A Protein
|
Below are MeSH descriptors whose meaning is more general than "rab3A GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "rab3A GTP-Binding Protein".
This graph shows the total number of publications written about "rab3A GTP-Binding Protein" by people in this website by year, and whether "rab3A GTP-Binding Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "rab3A GTP-Binding Protein" by people in Profiles.
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Hengel H, Hannan SB, Reich S, Beijer D, Roller J, Gilsbach BK, Gloeckner CJ, Greene D, Timmann D, Depienne C, Mumford A, O'Driscoll M, Nemeth AH, Lundberg J, Rodan LH, Bruel AL, Delanne J, Deconinck T, Baets J, Gan-Or Z, Rouleau G, Suchowersky O, Estiar MA, Reich S, Toro C, Z?chner S, Hazan J, P?tursson H, Harmuth F, Bauer C, Bauer P, Turro E, Lambright D, Sch?ls L, Synofzik M. Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism. Brain. 2025 Aug 01; 148(8):2812-2826.
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Bello OD, Cappa AI, de Paola M, Zanetti MN, Fukuda M, Fissore RA, Mayorga LS, Michaut MA. Rab3A, a possible marker of cortical granules, participates in cortical granule exocytosis in mouse eggs. Exp Cell Res. 2016 09 10; 347(1):42-51.
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Tomes CN, De Blas GA, Michaut MA, Farr? EV, Cherhitin O, Visconti PE, Mayorga LS. alpha-SNAP and NSF are required in a priming step during the human sperm acrosome reaction. Mol Hum Reprod. 2005 Jan; 11(1):43-51.
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Zhu Z, Delprato A, Merithew E, Lambright DG. Determinants of the broad recognition of exocytic Rab GTPases by Mss4. Biochemistry. 2001 Dec 25; 40(51):15699-706.
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Luo HR, Saiardi A, Nagata E, Ye K, Yu H, Jung TS, Luo X, Jain S, Sawa A, Snyder SH. GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase. Neuron. 2001 Aug 16; 31(3):439-51.
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Merithew E, Hatherly S, Dumas JJ, Lawe DC, Heller-Harrison R, Lambright DG. Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition. J Biol Chem. 2001 Apr 27; 276(17):13982-8.