"Cyclin T" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that is found associated with CYCLIN-DEPENDENT KINASE 9. Unlike traditional cyclins, which regulate the CELL CYCLE, type T cyclins appear to regulate transcription and are components of positive transcriptional elongation factor B.
| Descriptor ID |
D056906
|
| MeSH Number(s) |
D12.644.360.262.700 D12.776.167.218.700 D12.776.476.262.700 D12.776.930.955.500.249
|
| Concept/Terms |
Cyclin T- Cyclin T
- Type T Cyclin
- Cyclin, Type T
- Type T Cyclins
- Cyclins, Type T
|
Below are MeSH descriptors whose meaning is more general than "Cyclin T".
Below are MeSH descriptors whose meaning is more specific than "Cyclin T".
This graph shows the total number of publications written about "Cyclin T" by people in this website by year, and whether "Cyclin T" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin T" by people in Profiles.
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O'Brien SK, Cao H, Nathans R, Ali A, Rana TM. P-TEFb kinase complex phosphorylates histone H1 to regulate expression of cellular and HIV-1 genes. J Biol Chem. 2010 Sep 24; 285(39):29713-20.
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Chiu YL, Cao H, Rana TM. Quantitative analysis of RNA-mediated protein-protein interactions in living cells by FRET. Chem Biol Drug Des. 2007 Apr; 69(4):233-9.
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Chiu YL, Cao H, Jacque JM, Stevenson M, Rana TM. Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1). J Virol. 2004 Mar; 78(5):2517-29.
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Richter S, Cao H, Rana TM. Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation. Biochemistry. 2002 May 21; 41(20):6391-7.
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Zhang J, Tamilarasu N, Hwang S, Garber ME, Huq I, Jones KA, Rana TM. HIV-1 TAR RNA enhances the interaction between Tat and cyclin T1. J Biol Chem. 2000 Nov 03; 275(44):34314-9.