"Polymyxin B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
| Descriptor ID |
D011112
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| MeSH Number(s) |
D04.345.566.780.750 D10.477.750.750 D12.644.050.600.750 D12.644.641.780.750 D12.776.543.695.054.600.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polymyxin B".
Below are MeSH descriptors whose meaning is more specific than "Polymyxin B".
This graph shows the total number of publications written about "Polymyxin B" by people in this website by year, and whether "Polymyxin B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polymyxin B" by people in Profiles.
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Tomlinson G, Al-Khafaji A, Conrad SA, Factora FNF, Foster DM, Galphin C, Gunnerson KJ, Khan S, Kohli-Seth R, McCarthy P, Meena NK, Pearl RG, Rachoin JS, Rains R, Seneff M, Tidswell M, Walker PM, Kellum JA. Bayesian methods: a potential path forward for sepsis trials. Crit Care. 2023 11 08; 27(1):432.
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Lewis LA, Choudhury B, Balthazar JT, Martin LE, Ram S, Rice PA, Stephens DS, Carlson R, Shafer WM. Phosphoethanolamine substitution of lipid A and resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides and complement-mediated killing by normal human serum. Infect Immun. 2009 Mar; 77(3):1112-20.
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Finberg RW, Re F, Popova L, Golenbock DT, Kurt-Jones EA. Cell activation by Toll-like receptors: role of LBP and CD14. J Endotoxin Res. 2004; 10(6):413-8.
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Lynn WA, Golenbock DT. Lipopolysaccharide antagonists. Immunol Today. 1992 Jul; 13(7):271-6.
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Ellison RT, LaForce FM, Giehl TJ, Boose DS, Dunn BE. Lactoferrin and transferrin damage of the gram-negative outer membrane is modulated by Ca2+ and Mg2+. J Gen Microbiol. 1990 Jul; 136(7):1437-46.