Coculture Techniques

"Coculture Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A technique of culturing mixed cell types in vitro to allow their synergistic or antagonistic interactions, such as on CELL DIFFERENTIATION or APOPTOSIS. Coculture can be of different types of cells, tissues, or organs from normal or disease states.

Descriptor ID	D018920
MeSH Number(s)	E05.481.500.374
Concept/Terms	Coculture Techniques Coculture Techniques Coculture Technique Cocultivation Cocultivations Coculture Cocultures Co-culture Co culture Co-cultures

Below are MeSH descriptors whose meaning is more general than "Coculture Techniques".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
In Vitro Techniques [E05.481]
Culture Techniques [E05.481.500]
Coculture Techniques [E05.481.500.374]

Below are MeSH descriptors whose meaning is related to "Coculture Techniques".

Below are MeSH descriptors whose meaning is more specific than "Coculture Techniques".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Coculture Techniques" by people in this website by year, and whether "Coculture Techniques" was a major or minor topic of these publications.

Bar chart showing 88 publications over 29 distinct years, with a maximum of 9 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	0	1	1
1998	0	1	1
1999	0	1	1
2000	0	3	3
2001	0	2	2
2002	0	3	3
2003	0	4	4
2004	0	2	2
2005	1	3	4
2006	0	1	1
2007	0	1	1
2008	0	6	6
2009	0	4	4
2010	1	4	5
2011	0	9	9
2012	1	5	6
2013	0	6	6
2014	0	1	1
2015	0	7	7
2017	0	4	4
2018	1	2	3
2019	0	1	1
2020	0	2	2
2021	0	2	2
2023	0	1	1
2024	1	4	5
2025	0	1	1
2026	0	1	1

Below are the most recent publications written about "Coculture Techniques" by people in Profiles.

Callaghan NI, Durland LJ, Chen W, Kuzmanov U, Miranda MZ, Ding Y, Mirzaei Z, Ireland RG, Reitz C, Gorman RA, Wang EY, Wagner K, Kim MM, Audet J, Santerre JP, Gramolini AO, Billia F, Radisic M, Mital S, Ellis J, Backx PH, Simmons CA. Advanced physiological maturation of human iPSC-derived cardiomyocytes using an algorithm-directed optimization of defined media components. Nat Commun. 2026 Mar 31; 17(1).

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Baker V, Budinger D, Riechers SP, Heneka MT. Protocol for observing tunneling nanotube formation and function in both fixed and live primary mouse neurons and microglia coculture system. STAR Protoc. 2025 Jun 20; 6(2):103723.

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Bighetti-Trevisan RL, Almeida LO, Ramos JIR, Freitas GP, Oliveira FS, Gordon JAR, Tye CE, Stein GS, Lian JB, Stein JL, Rosa AL, Beloti MM. The effect of osteoclasts on epigenetic regulation by long non-coding RNAs in osteoblasts grown on titanium with nanotopography. Biomater Adv. 2025 Mar; 168:214128.

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Mishra AK, Banday S, Thakare RP, Malonia SK, Green MR. Protocol for monitoring phagocytosis of cancer cells by TAM-like macrophages using imaging cytometry. STAR Protoc. 2024 12 20; 5(4):103320.

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Struth E, Labaf M, Karimnia V, Liu Y, Cramer G, Dahl JB, Slack FJ, Zarringhalam K, Celli JP. Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models. Sci Rep. 2024 09 05; 14(1):20698.

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Scheiblich H, Eikens F, Wischhof L, Opitz S, J?ngling K, Cser?p C, Schmidt SV, Lambertz J, Bellande T, P?sfai B, Geck C, Spitzer J, Odainic A, Castro-Gomez S, Schwartz S, Boussaad I, Kr?ger R, Glaab E, Di Monte DA, Bano D, D?nes ?, Latz E, Melki R, Pape HC, Heneka MT. Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes. Neuron. 2024 09 25; 112(18):3106-3125.e8.

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Paulsen B, Piechota S, Barrachina F, Giovannini A, Kats S, Potts KS, Rockwell G, Marchante M, Estevez SL, Noblett AD, Figueroa AB, Aschenberger C, Kelk DA, Forti M, Marcinyshyn S, Wiemer K, Sanchez M, Belchin P, Lee JA, Buyuk E, Slifkin RE, Smela MP, Fortuna PRJ, Chatterjee P, McCulloh DH, Copperman AB, Ordonez-Perez D, Klein JU, Kramme CC. Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes. J Assist Reprod Genet. 2024 Aug; 41(8):2021-2036.

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Piechota S, Marchante M, Giovannini A, Paulsen B, Potts KS, Rockwell G, Aschenberger C, Noblett AD, Figueroa AB, Sanchez M, Barrachina F, Wiemer K, Guzman L, Belchin P, Pierson Smela M, Fortuna PRJ, Chatterjee P, Tran ND, Kelk DA, Forti M, Marcinyshyn S, Smith T, McCulloh DH, Fernandez-Gonzalez MJ, Abittan B, Ortiz S, Klein JU, Klatsky P, Ordonez-Perez D, Kramme CC. Human-induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation. Hum Reprod. 2023 12 04; 38(12):2456-2469.

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Wang EY, Kuzmanov U, Smith JB, Dou W, Rafatian N, Lai BFL, Lu RXZ, Wu Q, Yazbeck J, Zhang XO, Sun Y, Gramolini A, Radisic M. An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy. J Mol Cell Cardiol. 2021 11; 160:97-110.

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Li X, Henson MA. Dynamic metabolic modelling predicts efficient acetogen-gut bacterium cocultures for CO-to-butyrate conversion. J Appl Microbiol. 2021 Dec; 131(6):2899-2917.

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