O Antigens

"O Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)

Descriptor ID	D019081
MeSH Number(s)	D09.698.718.450.600 D10.494.600 D23.050.161.616.525.600 D23.946.123.329.500.600
Concept/Terms	O Antigens O Antigens Antigens, O O Antigen Antigen, O O-Specific Polysaccharides O Specific Polysaccharides Polysaccharides, O-Specific O-Specific Polysaccharide O Specific Polysaccharide Polysaccharide, O-Specific O Antigen, Bacterial Antigen, Bacterial O Bacterial O Antigen O-Antigens

Below are MeSH descriptors whose meaning is more general than "O Antigens".

Chemicals and Drugs [D]
Carbohydrates [D09]
Polysaccharides [D09.698]
Polysaccharides, Bacterial [D09.698.718]
Lipopolysaccharides [D09.698.718.450]
O Antigens [D09.698.718.450.600]
Lipids [D10]
Lipopolysaccharides [D10.494]
O Antigens [D10.494.600]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Bacterial [D23.050.161]
Polysaccharides, Bacterial [D23.050.161.616]
Lipopolysaccharides [D23.050.161.616.525]
O Antigens [D23.050.161.616.525.600]
Toxins, Biological [D23.946]
Bacterial Toxins [D23.946.123]
Endotoxins [D23.946.123.329]
Lipopolysaccharides [D23.946.123.329.500]
O Antigens [D23.946.123.329.500.600]

Below are MeSH descriptors whose meaning is related to "O Antigens".

Below are MeSH descriptors whose meaning is more specific than "O Antigens".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "O Antigens" by people in this website by year, and whether "O Antigens" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 1996 and 2007 and 2014 and 2017 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2007	1	0	1
2014	1	0	1
2017	0	1	1
2020	1	0	1

Below are the most recent publications written about "O Antigens" by people in Profiles.

Charles RC, Kelly M, Tam JM, Akter A, Hossain M, Islam K, Biswas R, Kamruzzaman M, Chowdhury F, Khan AI, Leung DT, Weil A, LaRocque RC, Bhuiyan TR, Rahman A, Mayo-Smith LM, Becker RL, Vyas JM, Faherty CS, Nickerson KP, Giffen S, Ritter AS, Waldor MK, Xu P, Kov?c P, Calderwood SB, Kauffman RC, Wrammert J, Qadri F, Harris JB, Ryan ET. Humans Surviving Cholera Develop Antibodies against Vibrio cholerae O-Specific Polysaccharide That Inhibit Pathogen Motility. mBio. 2020 11 17; 11(6).

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Piro AS, Hernandez D, Luoma S, Feeley EM, Finethy R, Yirga A, Frickel EM, Lesser CF, Coers J. Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility. mBio. 2017 12 12; 8(6).

View in: PubMed
Uddin T, Aktar A, Xu P, Johnson RA, Rahman MA, Leung DT, Afrin S, Akter A, Alam MM, Rahman A, Chowdhury F, Khan AI, Bhuiyan TR, Bufano MK, Rashu R, Yu Y, Wu-Freeman Y, Harris JB, LaRocque RC, Charles RC, Kov?c P, Calderwood SB, Ryan ET, Qadri F. Immune responses to O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 Ogawa in adult Bangladeshi recipients of an oral killed cholera vaccine and comparison to responses in patients with cholera. Am J Trop Med Hyg. 2014 May; 90(5):873-81.

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Miller WL, Matewish MJ, McNally DJ, Ishiyama N, Anderson EM, Brewer D, Brisson JR, Berghuis AM, Lam JS. Flagellin glycosylation in Pseudomonas aeruginosa PAK requires the O-antigen biosynthesis enzyme WbpO. J Biol Chem. 2008 Feb 08; 283(6):3507-3518.

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Donta ST, Peduzzi P, Cross AS, Sadoff J, Haakenson C, Cryz SJ, Kauffman C, Bradley S, Gafford G, Elliston D, Beam TR, John JF, Ribner B, Cantey R, Welsh CH, Ellison RT, Young EJ, Hamill RJ, Leaf H, Schein RM, Mulligan M, Johnson C, Abrutyn E, Griffiss JM, Slagle D, et al. Immunoprophylaxis against klebsiella and pseudomonas aeruginosa infections. The Federal Hyperimmune Immunoglobulin Trial Study Group. J Infect Dis. 1996 Sep; 174(3):537-43.

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Cross A, Artenstein A, Que J, Fredeking T, Furer E, Sadoff JC, Cryz SJ. Safety and immunogenicity of a polyvalent Escherichia coli vaccine in human volunteers. J Infect Dis. 1994 Oct; 170(4):834-40.

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