Antifibrinolytic Agents

"Antifibrinolytic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.

Descriptor ID	D000933
MeSH Number(s)	D27.505.519.421.500 D27.505.954.502.270.463.091
Concept/Terms	Antifibrinolytic Agents Antifibrinolytic Agents Agents, Antifibrinolytic Antifibrinolytics Antifibrinolysins Plasmin Inhibitors Plasmin Inhibitors Inhibitors, Plasmin Antiplasmins Plasmin Inhibitor Inhibitor, Plasmin

Below are MeSH descriptors whose meaning is more general than "Antifibrinolytic Agents".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Fibrin Modulating Agents [D27.505.519.421]
Antifibrinolytic Agents [D27.505.519.421.500]
Therapeutic Uses [D27.505.954]
Hematologic Agents [D27.505.954.502]
Coagulants [D27.505.954.502.270]
Hemostatics [D27.505.954.502.270.463]
Antifibrinolytic Agents [D27.505.954.502.270.463.091]

Below are MeSH descriptors whose meaning is related to "Antifibrinolytic Agents".

Below are MeSH descriptors whose meaning is more specific than "Antifibrinolytic Agents".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antifibrinolytic Agents" by people in this website by year, and whether "Antifibrinolytic Agents" was a major or minor topic of these publications.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 1998 and 2005 and 2012 and 2017 and 2018 and 2021 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2005	1	0	1
2012	0	1	1
2017	1	0	1
2018	1	0	1
2021	1	0	1
2024	1	0	1

Below are the most recent publications written about "Antifibrinolytic Agents" by people in Profiles.

Kumar EA, Morris LM, Michalski-McNeely BM. Tranexamic Acid in Mohs Micrographic Surgery: A Systematic Review. Dermatol Surg. 2025 01 01; 51(1):17-19.

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Hinson HE, Radabaugh HL, Li N, Fukuda T, Pollock J, Schreiber M, Rowell S, Ferguson AR. Predicting Progression of Intracranial Hemorrhage in the Prehospital TXA for TBI Trial. J Neurotrauma. 2024 10; 41(19-20):2349-2361.

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Tilvawala R, Nemmara VV, Reyes AC, Sorvillo N, Salinger AJ, Cherpokova D, Fukui S, Gutch S, Wagner D, Thompson PR. The role of SERPIN citrullination in thrombosis. Cell Chem Biol. 2021 12 16; 28(12):1728-1739.e5.

View in: PubMed
Holley SL, Green K, Mills M, Detterman C, Rappold MF, Thayer S. Educating Parents on Vitamin K Prophylaxis for Newborns. Nurs Womens Health. 2020 Aug; 24(4):283-293.

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Walsh SLF, Lederer DJ, Ryerson CJ, Kolb M, Maher TM, Nusser R, Poletti V, Richeldi L, Vancheri C, Wilsher ML, Antoniou KM, Behr J, Bendstrup E, Brown KK, Corte TJ, Cottin V, Crestani B, Flaherty KR, Glaspole IN, Grutters J, Inoue Y, Kondoh Y, Kreuter M, Johannson KA, Ley B, Martinez FJ, Molina-Molina M, Morais A, Nunes H, Raghu G, Selman M, Spagnolo P, Taniguchi H, Tomassetti S, Valeyre D, Wijsenbeek M, Wuyts WA, Wells AU. Diagnostic Likelihood Thresholds That Define a Working Diagnosis of Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 11 01; 200(9):1146-1153.

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Ayers DC. Tranexamic Acid: Both Efficacious and Safe When Used in Total Hip Arthroplasty to Reduce Blood Transfusions: Commentary on an article by Alexander Dastrup, MD, et al.: "Perioperative Tranexamic Acid Treatment and Risk of Cardiovascular Events or Death After Total Hip Arthroplasty. A Population-Based Cohort Study from National Danish Databases". J Bone Joint Surg Am. 2018 10 17; 100(20):e135.

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Howard JT, Stockinger ZT, Cap AP, Bailey JA, Gross KR. Military use of tranexamic acid in combat trauma: Does it matter? J Trauma Acute Care Surg. 2017 10; 83(4):579-588.

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Mitra B, Mazur S, Cameron PA, Bernard S, Burns B, Smith A, Rashford S, Fitzgerald M, Smith K, Gruen RL. Tranexamic acid for trauma: filling the 'GAP' in evidence. Emerg Med Australas. 2014 Apr; 26(2):194-7.

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Matteson KA, Rahn DD, Wheeler TL, Casiano E, Siddiqui NY, Harvie HS, Mamik MM, Balk EM, Sung VW. Nonsurgical management of heavy menstrual bleeding: a systematic review. Obstet Gynecol. 2013 Mar; 121(3):632-643.

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Loke C, Ali SS, Johari V. Pharmacology of anticoagulants. Dis Mon. 2012 Aug; 58(8):424-30.

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