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SFRP1 decreases WNT-Mediated M2 macrophage marker expression in breast tissue.
Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikis.
Mice deficient in Sfrp1 exhibit increased adiposity, dysregulated glucose metabolism, and enhanced macrophage infiltration.
High-Precision Micro-Total Analysis of Sodium Ions in Breast Milk.
Loss of SFRP1 promotes ductal branching in the murine mammary gland.
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Loss of SFRP1 promotes ductal branching in the murine mammary gland.
Gauger KJ, Shimono A, Crisi GM, Schneider SS. Loss of SFRP1 promotes ductal branching in the murine mammary gland. BMC Dev Biol. 2012 Aug 28; 12:25.
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PubMed
subject areas
Animals
Axin Protein
Cells, Cultured
Epithelial Cells
Female
Intercellular Signaling Peptides and Proteins
Mammary Glands, Animal
Membrane Proteins
Mice
Mice, Knockout
Morphogenesis
Phenotype
Pregnancy
Proto-Oncogene Proteins c-myc
Spheroids, Cellular
Transcriptome
Wnt Proteins
authors with profiles
Giovanna M Crisi MD, PhD
Sallie Smith Schneider PhD