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A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage.
Exclusion of older adults and women from recent trials of acute coronary syndromes.
Herpes simplex virus and toll-like receptors.
JunD mediates survival signaling by the JNK signal transduction pathway.
Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance.
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JunD mediates survival signaling by the JNK signal transduction pathway.
Lamb JA, Ventura JJ, Hess P, Flavell RA, Davis RJ. JunD mediates survival signaling by the JNK signal transduction pathway. Mol Cell. 2003 Jun; 11(6):1479-89.
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PubMed
subject areas
Animals
Apoptosis
Cell Line
Cell Survival
DNA Fragmentation
Enzyme Activation
Fibroblasts
Gene Expression Regulation
Genes, Reporter
Mice
Mitogen-Activated Protein Kinases
Models, Biological
NF-kappa B
Protein Isoforms
Proto-Oncogene Proteins c-jun
Signal Transduction
Time Factors
Transcription, Genetic
Tumor Necrosis Factor-alpha
authors with profiles
Roger J Davis PhD, FRS