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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.
The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation.
Adenovirus early region 3 transgenes expressed in beta cells prevent autoimmune diabetes in nonobese diabetic mice: effects of deleting the adenovirus death protein 11.6K.
Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes.
Endotoxin recognition and signal transduction by the TLR4/MD2-complex.
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Endotoxin recognition and signal transduction by the TLR4/MD2-complex.
Fitzgerald KA, Rowe DC, Golenbock DT. Endotoxin recognition and signal transduction by the TLR4/MD2-complex. Microbes Infect. 2004 Dec; 6(15):1361-7.
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PubMed
subject areas
Animals
Antigens, Surface
Carrier Proteins
Endotoxins
Lipopolysaccharides
Lymphocyte Antigen 96
Membrane Glycoproteins
Receptors, Cell Surface
Signal Transduction
Toll-Like Receptor 4
Toll-Like Receptors
authors with profiles
Katherine A Fitzgerald PhD
Douglas T Golenbock MD