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Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs inhibit AIM2 inflammasome activation.
The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence.
An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual.
A TIR domain variant of MyD88 adapter-like (Mal)/TIRAP results in loss of MyD88 binding and reduced TLR2/TLR4 signaling.
Immunology: Lipopolysaccharide sensing on the inside.
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Immunology: Lipopolysaccharide sensing on the inside.
Rathinam VA, Fitzgerald KA. Immunology: Lipopolysaccharide sensing on the inside. Nature. 2013 Sep 12; 501(7466):173-5.
View in:
PubMed
subject areas
Animals
Caspases
Caspases, Initiator
Cytoplasm
Gram-Negative Bacteria
Humans
Immunity, Innate
Inflammasomes
Lipopolysaccharides
Mice
Toll-Like Receptor 4
authors with profiles
Katherine A Fitzgerald PhD