Central Nervous System

"Central Nervous System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.

Descriptor ID	D002490
MeSH Number(s)	A08.186
Concept/Terms	Central Nervous System Central Nervous System Central Nervous Systems Nervous System, Central Nervous Systems, Central System, Central Nervous Systems, Central Nervous Cerebrospinal Axis Axi, Cerebrospinal Axis, Cerebrospinal Cerebrospinal Axi

Below are MeSH descriptors whose meaning is more general than "Central Nervous System".

Anatomy [A]
Nervous System [A08]
Central Nervous System [A08.186]

Below are MeSH descriptors whose meaning is related to "Central Nervous System".

Below are MeSH descriptors whose meaning is more specific than "Central Nervous System".

Central Nervous System
Brain
Meninges
Spinal Cord

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Central Nervous System" by people in this website by year, and whether "Central Nervous System" was a major or minor topic of these publications.

Bar chart showing 104 publications over 30 distinct years, with a maximum of 7 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	2	2
1996	0	1	1
1997	2	0	2
1998	1	1	2
1999	0	2	2
2000	1	1	2
2001	0	2	2
2002	3	0	3
2003	3	1	4
2004	1	0	1
2005	3	4	7
2006	3	3	6
2007	1	2	3
2009	1	0	1
2010	4	0	4
2011	4	2	6
2012	4	0	4
2013	5	1	6
2014	4	1	5
2015	4	2	6
2016	2	0	2
2017	0	2	2
2018	2	0	2
2019	3	3	6
2020	1	2	3
2021	2	2	4
2022	1	2	3
2023	1	5	6
2024	4	2	6

Below are the most recent publications written about "Central Nervous System" by people in Profiles.

Belgrad J, Tang Q, Hildebrand S, Summers A, Sapp E, Echeverria D, O'Reilly D, Luu E, Bramato B, Allen S, Cooper D, Alterman J, Yamada K, Aronin N, DiFiglia M, Khvorova A. A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system. Nucleic Acids Res. 2024 Jun 24; 52(11):6099-6113.

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Ferguson CM, Godinho BMDC, Echeverria D, Hassler M, Vangjeli L, Sousa J, McHugh N, Alterman J, Hariharan V, Krishnamurthy PM, Watts J, Rogaev E, Khvorova A. A combinatorial approach for achieving CNS-selective RNAi. Nucleic Acids Res. 2024 May 22; 52(9):5273-5284.

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Beiter RM, Sheehan PW, Schafer DP. Microglia phagocytic mechanisms: Development informing disease. Curr Opin Neurobiol. 2024 Jun; 86:102877.

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Das S, Rruga F, Montepeloso A, Dimartino A, Spadini S, Corre G, Patel J, Cavalca E, Ferro F, Gatti A, Milazzo R, Galy A, Politi LS, Rizzardi GP, Vallanti G, Poletti V, Biffi A. An empowered, clinically viable hematopoietic stem cell gene therapy for the treatment of multisystemic mucopolysaccharidosis type II. Mol Ther. 2024 Mar 06; 32(3):619-636.

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Dur?n Laforet V, Schafer DP. Microglia: Activity-dependent regulators of neural circuits. Ann N Y Acad Sci. 2024 03; 1533(1):38-50.

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Daci R, Flotte TR. Delivery of Adeno-Associated Virus Vectors to the Central Nervous System for Correction of Single Gene Disorders. Int J Mol Sci. 2024 Jan 15; 25(2).

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Stillman JM, Mendes Lopes F, Lin JP, Hu K, Reich DS, Schafer DP. Lipofuscin-like autofluorescence within microglia and its impact on studying microglial engulfment. Nat Commun. 2023 11 03; 14(1):7060.

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Zhang W, Oh JH, Zhang W, Rathi S, Larson JD, Wechsler-Reya RJ, Sirianni RW, Elmquist WF. Central Nervous System Distribution of Panobinostat in Preclinical Models to Guide Dosing for Pediatric Brain Tumors. J Pharmacol Exp Ther. 2023 12; 387(3):315-327.

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Johnson AK, McCurdy VJ, Gray-Edwards HL, Maguire AS, Cochran JN, Gross AL, Skinner HE, Randle AN, Shirley JL, Brunson BL, Bradbury AM, Leroy SG, Hwang M, Rockwell HE, Cox NR, Baker HJ, Seyfried TN, Sena-Esteves M, Martin DR. Life-Limiting Peripheral Organ Dysfunction in Feline Sandhoff Disease Emerges after Effective CNS Gene Therapy. Ann Neurol. 2023 11; 94(5):969-986.

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Walker KA, Le Page LM, Terrando N, Duggan MR, Heneka MT, Bettcher BM. The role of peripheral inflammatory insults in Alzheimer's disease: a review and research roadmap. Mol Neurodegener. 2023 06 05; 18(1):37.

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