Nucleic Acid Heteroduplexes
"Nucleic Acid Heteroduplexes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
| Descriptor ID |
D009692
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| MeSH Number(s) |
D13.444.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Heteroduplexes".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Heteroduplexes".
This graph shows the total number of publications written about "Nucleic Acid Heteroduplexes" by people in this website by year, and whether "Nucleic Acid Heteroduplexes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nucleic Acid Heteroduplexes" by people in Profiles.
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Samanta S, Martin CT. Insights into the mechanism of initial transcription in Escherichia coli RNA polymerase. J Biol Chem. 2013 Nov 01; 288(44):31993-2003.
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Liu X, Martin CT. Transcription elongation complex stability: the topological lock. J Biol Chem. 2009 Dec 25; 284(52):36262-36270.
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Liu X, Nakamura K, Wang Y, Zhang S, He J, Liu G, Dou S, Kubo A, Rusckowski M, Hnatowich D. Improved delivery in cell culture of radiolabeled antisense DNAs by duplex formation. Mol Imaging Biol. 2006 Sep-Oct; 8(5):278-83.
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Ping YH, Rana TM. Mechanism of site-specific psoralen photoadducts formation in triplex DNA directed by psoralen-conjugated oligonucleotides. Biochemistry. 2005 Feb 22; 44(7):2501-9.
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Cannon W, Gallegos MT, Casaz P, Buck M. Amino-terminal sequences of sigmaN (sigma54) inhibit RNA polymerase isomerization. Genes Dev. 1999 Feb 01; 13(3):357-70.
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Gaywee J, Artenstein AW, VanCott TC, Trichavaroj R, Sukchamnong A, Amlee P, de Souza M, McCutchan FE, Carr JK, Markowitz LE, Michael R, Nittayaphan S. Correlation of genetic and serologic approaches to HIV-1 subtyping in Thailand. J Acquir Immune Defic Syndr Hum Retrovirol. 1996 Dec 01; 13(4):392-6.
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Fathi R, Huang Q, Coppola G, Delaney W, Teasdale R, Krieg AM, Cook AF. Oligonucleotides with novel, cationic backbone substituents: aminoethylphosphonates. Nucleic Acids Res. 1994 Dec 11; 22(24):5416-24.
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Carraway M, Marinus MG. Repair of heteroduplex DNA molecules with multibase loops in Escherichia coli. J Bacteriol. 1993 Jul; 175(13):3972-80.