Myelin Sheath

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"Myelin Sheath" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.

Descriptor ID	D009186
MeSH Number(s)	A08.637.600.500 A08.637.800.500 A08.675.542.512.560 A08.800.800.690.500 A10.755.503 A11.284.149.165.600 A11.650.600.500 A11.650.800.500 A11.671.501.512.560 A11.671.514.553
Concept/Terms	Myelin Sheath Myelin Sheath Myelin Sheaths Sheath, Myelin Sheaths, Myelin Myelin Myelin

Below are MeSH descriptors whose meaning is more general than "Myelin Sheath".

Anatomy [A]
Nervous System [A08]
Neuroglia [A08.637]
Oligodendroglia [A08.637.600]
Myelin Sheath [A08.637.600.500]
Schwann Cells [A08.637.800]
Myelin Sheath [A08.637.800.500]
Neurons [A08.675]
Nerve Fibers [A08.675.542]
Nerve Fibers, Myelinated [A08.675.542.512]
Myelin Sheath [A08.675.542.512.560]
Peripheral Nervous System [A08.800]
Peripheral Nerves [A08.800.800]
Schwann Cells [A08.800.800.690]
Myelin Sheath [A08.800.800.690.500]
Tissues [A10]
Nerve Tissue [A10.755]
Myelin Sheath [A10.755.503]
Cells [A11]
Cellular Structures [A11.284]
Cell Membrane [A11.284.149]
Cell Membrane Structures [A11.284.149.165]
Myelin Sheath [A11.284.149.165.600]
Neuroglia [A11.650]
Oligodendroglia [A11.650.600]
Myelin Sheath [A11.650.600.500]
Schwann Cells [A11.650.800]
Myelin Sheath [A11.650.800.500]
Neurons [A11.671]
Nerve Fibers [A11.671.501]
Nerve Fibers, Myelinated [A11.671.501.512]
Myelin Sheath [A11.671.501.512.560]
Nerve Fibers, Myelinated [A11.671.514]
Myelin Sheath [A11.671.514.553]

Below are MeSH descriptors whose meaning is related to "Myelin Sheath".

Below are MeSH descriptors whose meaning is more specific than "Myelin Sheath".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Myelin Sheath" by people in this website by year, and whether "Myelin Sheath" was a major or minor topic of these publications.

Bar chart showing 1 publications over 1 distinct years, with a maximum of 1 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2013	1	0	1

Below are the most recent publications written about "Myelin Sheath" by people in Profiles.

Tian F, Yang W, Mordes DA, Wang JY, Salameh JS, Mok J, Chew J, Sharma A, Leno-Duran E, Suzuki-Uematsu S, Suzuki N, Han SS, Lu FK, Ji M, Zhang R, Liu Y, Strominger J, Shneider NA, Petrucelli L, Xie XS, Eggan K. Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging. Nat Commun. 2016 10 31; 7:13283.

View in: PubMed
Lugar HM, Koller JM, Rutlin J, Marshall BA, Kanekura K, Urano F, Bischoff AN, Shimony JS, Hershey T. Neuroimaging evidence of deficient axon myelination in Wolfram syndrome. Sci Rep. 2016 Feb 18; 6:21167.

View in: PubMed
Chen CD, Sloane JA, Li H, Aytan N, Giannaris EL, Zeldich E, Hinman JD, Dedeoglu A, Rosene DL, Bansal R, Luebke JI, Kuro-o M, Abraham CR. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. J Neurosci. 2013 Jan 30; 33(5):1927-39.

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Sparrow N, Manetti ME, Bott M, Fabianac T, Petrilli A, Bates ML, Bunge MB, Lambert S, Fernandez-Valle C. The actin-severing protein cofilin is downstream of neuregulin signaling and is essential for Schwann cell myelination. J Neurosci. 2012 Apr 11; 32(15):5284-97.

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Thaxton C, Bott M, Walker B, Sparrow NA, Lambert S, Fernandez-Valle C. Schwannomin/merlin promotes Schwann cell elongation and influences myelin segment length. Mol Cell Neurosci. 2011 May; 47(1):1-9.

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Lopez-Larson M, Breeze JL, Kennedy DN, Hodge SM, Tang L, Moore C, Giuliano AJ, Makris N, Caviness VS, Frazier JA. Age-related changes in the corpus callosum in early-onset bipolar disorder assessed using volumetric and cross-sectional measurements. Brain Imaging Behav. 2010 Dec; 4(3-4):220-31.

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Doherty J, Logan MA, Tasdemir OE, Freeman MR. Ensheathing glia function as phagocytes in the adult Drosophila brain. J Neurosci. 2009 Apr 15; 29(15):4768-81.

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Arroyo EJ, Xu T, Grinspan J, Lambert S, Levinson SR, Brophy PJ, Peles E, Scherer SS. Genetic dysmyelination alters the molecular architecture of the nodal region. J Neurosci. 2002 Mar 01; 22(5):1726-37.

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Kaye EM, Alroy J, Raghavan SS, Schwarting GA, Adelman LS, Runge V, Gelblum D, Thalhammer JG, Zuniga G. Dysmyelinogenesis in animal model of GM1 gangliosidosis. Pediatr Neurol. 1992 Jul-Aug; 8(4):255-61.

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Nave KA, Lai C, Bloom FE, Milner RJ. Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin. Proc Natl Acad Sci U S A. 1987 Aug; 84(16):5665-9.

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