Receptors, Antigen, T-Cell

"Receptors, Antigen, T-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.

Descriptor ID	D011948
MeSH Number(s)	D12.776.543.750.705.816.824
Concept/Terms	Receptors, Antigen, T-Cell Receptors, Antigen, T-Cell T-Cell Antigen Receptor Antigen Receptor, T-Cell Receptor, T-Cell Antigen T Cell Antigen Receptor T-Cell Receptors Receptors, T-Cell T Cell Receptors T-Cell Receptor Receptor, T-Cell T Cell Receptor Receptors, T-Cell Antigen Receptors, T Cell Antigen T-Cell Antigen Receptors Antigen Receptors, T-Cell Antigen Receptors, T Cell

Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, T-Cell".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Antigen [D12.776.543.750.705.816]
Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]

Below are MeSH descriptors whose meaning is related to "Receptors, Antigen, T-Cell".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, T-Cell".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Antigen, T-Cell" by people in this website by year, and whether "Receptors, Antigen, T-Cell" was a major or minor topic of these publications.

Bar chart showing 206 publications over 30 distinct years, with a maximum of 16 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	2	4
1997	5	2	7
1998	4	5	9
1999	6	3	9
2001	0	2	2
2002	1	7	8
2003	1	1	2
2004	3	13	16
2005	6	4	10
2006	5	5	10
2007	3	2	5
2008	5	4	9
2009	2	7	9
2010	6	6	12
2011	1	0	1
2012	4	3	7
2013	2	5	7
2014	4	8	12
2015	6	2	8
2016	2	4	6
2017	8	0	8
2018	2	4	6
2019	1	1	2
2020	1	2	3
2021	6	1	7
2022	2	7	9
2023	0	9	9
2024	1	2	3
2025	4	1	5
2026	1	0	1

Below are the most recent publications written about "Receptors, Antigen, T-Cell" by people in Profiles.

Gaglione SA, Mukkamala RS, Krishna C, Smith BE, Wadsworth MH, Jelinsky SA, Perez CR, Schmidt-Hong L, Katz EL, Gellatly KJ, Ali LR, Shen J, Holec PV, Zhao QH, Chan AO, Xu EJK, Kravarik KM, Guzova JA, Dobson CS, Singh H, Garber M, Dougan M, Dougan SK, Harris JE, Winkler A, Birnbaum ME. Scalable TCR synthesis and screening enable antigen reactivity mapping in vitiligo. Immunity. 2026 Feb 10; 59(2):477-493.e9.

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Becerra-Artiles A, Weaver GC, Oluoch PO, Stern LJ. TCR repertoire of human cytotoxic CD4 T cells responding to betaherpesviruses HHV-6B and HCMV. Front Immunol. 2025; 16:1631558.

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Murata K, Minowa T, Tsukahara T, Yoshida T, Minami A, Nakatsugawa M, Mizue Y, Murai A, Tokita S, Sasaki K, Uhara H, Kubo T, Kanaseki T, Torigoe T, Hirohashi Y. An SNP-dependent cancer-testis antigenic epitope serves as a promising immunotherapeutic target for cancer. Oncoimmunology. 2025 Dec; 14(1):2528110.

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Croce G, Lani R, Tardivon D, Bobisse S, de Tiani M, Bragina M, Perez MAS, Michaux J, Pak HS, Michel A, Gehret T, Schmidt J, Guillame P, Bassani-Sternberg M, Zoete V, Harari A, Rufer N, Hebeisen M, Dunn SM, Gfeller D. Phage display enables machine learning discovery of cancer antigen-specific TCRs. Sci Adv. 2025 Jun 13; 11(24):eads5589.

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Day-Lewis ME, Berbert L, DeGrazia M, Yee C, Fried AJ, Nguyen AA, Hale JE, Counihan A, Comeau AM, Treffeisen ER, Reed MP, Platt CD, Chou J. Incidence and risk factors for CMV and EBV infection in infants with low T-cell receptor excision circles on newborn screen. Clin Immunol. 2025 Aug; 277:110510.

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Seamann A, Bennett-Boehm M, Ehrlich R, Gil A, Selin L, Ghersi D. TRain: T-cell receptor automated immunoinformatics. BMC Bioinformatics. 2025 Mar 06; 26(1):76.

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Lo WL, Huseby ES. The partitioning of TCR repertoires by thymic selection. J Exp Med. 2024 Oct 07; 221(10).

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Shi Y, Strasser A, Green DR, Latz E, Mantovani A, Melino G. Legacy of the discovery of the T-cell receptor: 40 years of shaping basic immunology and translational work to develop novel therapies. Cell Mol Immunol. 2024 Jul; 21(7):790-797.

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Lin Y, Qiu L, Usmani S, Joo CW, Costa L, Derman B, Du J, Einsele H, Fernandez de Larrea C, Hajek R, Ho PJ, Kastritis E, Martinez-Lopez J, Mateos MV, Mikhael J, Moreau P, Nagarajan C, Nooka A, O'Dwyer M, Schjesvold F, Sidana S, van de Donk NW, Weisel K, Zweegman S, Raje N, Otero PR, Anderson LD, Kumar S, Martin T. Consensus guidelines and recommendations for the management and response assessment of chimeric antigen receptor T-cell therapy in clinical practice for relapsed and refractory multiple myeloma: a report from the International Myeloma Working Group Immunotherapy Committee. Lancet Oncol. 2024 08; 25(8):e374-e387.

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Racine JJ, Misherghi A, Dwyer JR, Maser R, Forte E, Bedard O, Sattler S, Pugliese A, Landry L, Elso C, Nakayama M, Mannering S, Rosenthal N, Serreze DV. HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice. J Immunol. 2023 12 15; 211(12):1792-1805.

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